NDLI: Evaluating the respiratory bioaccessibility of nickel in soil through the use of a simulated lung fluid

Content Provider	Springer Nature Link
Author	Drysdale, Mallory Ljung Bjorklund, Karin Jamieson, Heather E. Weinstein, Philip Cook, Angus Watkins, Ron T.
Copyright Year	2011
Abstract	Simulated lung fluids are solutions designed to mimic the composition of human interstitial lung fluid as closely as possible. Analysis of mineral dusts using such solutions has been used to evaluate the respiratory bioaccessibility of various elements for which solubility in the lungs is a primary determinant of reactivity. The objective of this study was to employ simulated lung fluid analysis to investigate the respiratory bioaccessibility of nickel in soils. Current occupational guidelines in Australia regulate nickel compounds in terms of water solubility, though this may not be an accurate estimation of the total nickel that will dissociate in the lungs. Surface soils were collected from the city of Kalgoorlie in Western Australia, the site of an operational nickel smelter and metal mining activities. The fraction of the samples less than 10 μm was extracted from the soil, and it was this sub-10-μm fraction that was found to hold most of the total nickel present in the soil. The fine fraction was analyzed using a simulated lung fluid (modified Gamble’s solution) to isolate the nickel phases soluble in the lungs. In addition, a sequential extraction was employed to compare the bioaccessible fraction to those dissolved from different binding forms in the soil. In all samples, the simulated lung fluid extracted more nickel than the two weakest leaches of the sequential extraction combined, providing a more representative nickel bioaccessibility value than the current water leach method.
Starting Page	279
Ending Page	288
Page Count	10
File Format	PDF
ISSN	02694042
Journal	Environmental Geochemistry and Health
Volume Number	34
Issue Number	2
e-ISSN	15732983
Language	English
Publisher	Springer Netherlands
Publisher Date	2011-10-09
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Dust Nickel Smelter Simulated lung fluid Public Health/Gesundheitswesen Terrestrial Pollution Geochemistry Environmental Chemistry Soil Science & Conservation Environmental Health
Content Type	Text
Resource Type	Article
Subject	Environmental Chemistry Medicine Geochemistry and Petrology Environmental Engineering Water Science and Technology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Oral bioaccessibility of trace metals in household dust: a review

Assessing Cd, Pb, Zn human bioaccessibility in smelter-contaminated agricultural topsoils (northern France)

Chemical speciation and bioaccessibility of lead in surface soil and house dust, Lavrion urban area, Attiki, Hellas

Dust from Zambian smelters: mineralogy and contaminant bioaccessibility

Evaluating the respiratory bioaccessibility of nickel in soil through the use of a simulated lung fluid.

Lead availability in soils from Portugal’s Centre Region with special reference to bioaccessibility

Relative bioaccessibility of Pb-based paint in soil

Combining spatial distribution with oral bioaccessibility of metals in smelter-impacted soils: implications for human health risk assessment

Oral bioaccessibility of metals in an urban catchment, Newcastle upon Tyne

Evaluating the respiratory bioaccessibility of nickel in soil through the use of a simulated lung fluid

Similar Documents

Oral bioaccessibility of trace metals in household dust: a review

Assessing Cd, Pb, Zn human bioaccessibility in smelter-contaminated agricultural topsoils (northern France)

Chemical speciation and bioaccessibility of lead in surface soil and house dust, Lavrion urban area, Attiki, Hellas

Dust from Zambian smelters: mineralogy and contaminant bioaccessibility

Evaluating the respiratory bioaccessibility of nickel in soil through the use of a simulated lung fluid.

Lead availability in soils from Portugal’s Centre Region with special reference to bioaccessibility

Relative bioaccessibility of Pb-based paint in soil

Combining spatial distribution with oral bioaccessibility of metals in smelter-impacted soils: implications for human health risk assessment

Oral bioaccessibility of metals in an urban catchment, Newcastle upon Tyne

Evaluating the respiratory bioaccessibility of nickel in soil through the use of a simulated lung fluid