NDLI: Temporal trends in the black/white breast cancer case ratio for estrogen receptor status: disparities are historically contingent, not innate

Content Provider	Springer Nature Link
Author	Krieger, Nancy Chen, Jarvis T. Waterman, Pamela D.
Copyright Year	2010
Abstract	For at least three decades, many investigators have reported on the US black/white breast cancer case ratio for estrogen receptor (ER) status as if it reflected an intrinsic biological difference. In light of racial/ethnic differences in declines in the incidence of ER+ breast cancer, as linked to changing use of hormone therapy, we empirically tested whether the black/white breast cancer estrogen receptor ratio has changed over time.We examined temporal trends in the odds of being ER+ among white as compared to black women among all cases of invasive breast cancer occurring among women residing in the catchment area of the SEER 13 Registries Database between 1992 and 2005.During the study period, the odds of being ER+ among the white compared to black cases increased from 1992 to 2002 (a statistically significant joinpoint; p < 0.05; peak odds ratio (2002) = 2.25 (95% confidence interval 2.13, 2.39)). Thereafter, the odds ratio leveled off (post-2002 slope not significantly different from zero; p = 0.326). Among women aged 45–54, moreover, the post-2002 decline tended toward statistical significance (p = 0.0891).The results suggest the black/white breast cancer case estrogen receptor ratio is historically contingent, not innate.
Starting Page	511
Ending Page	514
Page Count	4
File Format	PDF
ISSN	09575243
Journal	Cancer Causes & Control
Volume Number	22
Issue Number	3
e-ISSN	15737225
Language	English
Publisher	Springer Netherlands
Publisher Date	2010-12-25
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Black Breast cancer Cancer disparities Estrogen receptor Social determinants of health White Public Health/Gesundheitswesen Cancer Research Hematology Epidemiology Oncology Biomedicine general
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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Temporal trends in the black/white breast cancer case ratio for estrogen receptor status: disparities are historically contingent, not innate

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Temporal trends in the black/white breast cancer case ratio for estrogen receptor status: disparities are historically contingent, not innate

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Temporal trends in the black/white breast cancer case ratio for estrogen receptor status: disparities are historically contingent, not innate

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Temporal trends in the black/white breast cancer case ratio for estrogen receptor status: disparities are historically contingent, not innate