NDLI: Association between tobacco use and the upper gastrointestinal microbiome among Chinese men

Content Provider	Springer Nature Link
Author	Vogtmann, Emily Flores, Roberto Yu, Guoqin Freedman, Neal D. Shi, Jianxin Gail, Mitchell H. Dye, Bruce A. Wang, Guo Qing Klepac Ceraj, Vanja Paster, Bruce J. Wei, Wen Qiang Guo, Hui Qin Dawsey, Sanford M. Qiao, You Lin Abnet, Christian C.
Copyright Year	2015
Abstract	Tobacco causes many adverse health conditions and may alter the upper gastrointestinal (UGI) microbiome. However, the few studies that studied the association between tobacco use and the microbiome were small and underpowered. Therefore, we investigated the association between tobacco use and the UGI microbiome in Chinese men.We included 278 men who underwent esophageal cancer screening in Henan Province, China. Men were categorized as current, former, or never smokers from questionnaire data. UGI tract bacterial cells were characterized using the Human Oral Microbial Identification Microarray. Counts of unique bacterial species and genera estimated alpha diversity. For beta diversity, principal coordinate (PCoA) vectors were generated from an unweighted UniFrac distance matrix. Polytomous logistic regression models were used for most analyses.Of the 278 men in this study, 46.8 % were current smokers and 12.6 % were former smokers. Current smokers tended to have increased alpha diversity (mean 42.3 species) compared to never smokers (mean 38.9 species). For a 10 species increase, the odds ratio (OR) for current smoking was 1.29 (95 % CI 1.04–1.62). Beta diversity was also associated with current smoking. The first two PCoA vectors were strongly associated with current smoking (PCoA1 OR 0.66; 95 % CI 0.51–0.87; PCoA2 OR 0.73; 95 % CI 0.56–0.95). Furthermore, Dialister invisus and Megasphaera micronuciformis were more commonly detected in current smokers than in never smokers.Current smoking was associated with both alpha and beta diversity in the UGI tract. Future work should consider how the UGI microbiome is associated with smoking-related diseases.
Starting Page	581
Ending Page	588
Page Count	8
File Format	PDF
ISSN	09575243
Journal	Cancer Causes & Control
Volume Number	26
Issue Number	4
e-ISSN	15737225
Language	English
Publisher	Springer International Publishing
Publisher Date	2015-02-21
Publisher Place	Cham
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	China Microbiome Tobacco Upper gastrointestinal tract Cancer Research Biomedicine general Oncology Public Health Epidemiology Hematology
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Association between tobacco use and the upper gastrointestinal microbiome among Chinese men

The aetiology of upper aerodigestive tract cancers among young adults in Europe: the ARCAGE study

Oral microbiome and oral and gastrointestinal cancer risk

Alcohol and tobacco, and the risk of cancers of the upper aerodigestive tract in Latin America: a case–control study

Jasmine tea consumption and upper gastrointestinal cancer in China

Tobacco use among low-income housing residents: does hardship motivate quit attempts?

Erratum to: Association of sugary beverages with survival among patients with cancers of the upper aerodigestive tract

Tobacco smoking, NBS1 polymorphisms, and survival in lung and upper aerodigestive tract cancers with semi-Bayes adjustment for hazard ratio variation

Alcohol, marijuana, and tobacco use patterns among youth in Canada

Association between tobacco use and the upper gastrointestinal microbiome among Chinese men

Similar Documents

Association between tobacco use and the upper gastrointestinal microbiome among Chinese men

The aetiology of upper aerodigestive tract cancers among young adults in Europe: the ARCAGE study

Oral microbiome and oral and gastrointestinal cancer risk

Alcohol and tobacco, and the risk of cancers of the upper aerodigestive tract in Latin America: a case–control study

Jasmine tea consumption and upper gastrointestinal cancer in China

Tobacco use among low-income housing residents: does hardship motivate quit attempts?

Erratum to: Association of sugary beverages with survival among patients with cancers of the upper aerodigestive tract

Tobacco smoking, NBS1 polymorphisms, and survival in lung and upper aerodigestive tract cancers with semi-Bayes adjustment for hazard ratio variation

Alcohol, marijuana, and tobacco use patterns among youth in Canada

Association between tobacco use and the upper gastrointestinal microbiome among Chinese men