NDLI: Greater intake of fruit and vegetables is associated with lower risk of nasopharyngeal carcinoma in Chinese adults: a case

Content Provider	Springer Nature Link
Author	Liu, Yuan ting Dai, Jun jin Xu, Chun hua Lu, Yun kai Fan, Yu ying Zhang, Xing lan Zhang, Cai xia Chen, Yu ming
Copyright Year	2012
Abstract	The effect of fruit and vegetable intake on the risk of nasopharyngeal carcinoma (NPC) remains uncertain due to limited published evidence. We performed a matched case–control study to investigate the relationship between the intake of fruit and vegetables and the risk of NPC.Between July 2009 and March 2011, 600 (448 male, 152 female), NPC incident cases from a single hospital in Guangzhou, Guangdong Province, China, a high-incidence area, were enrolled in the study. 600 controls, matched by gender, age (±3 years) and household type (urban/rural) were also enrolled. Face-to-face interviews were used to collect habitual dietary intakes and information on various covariates.Multivariate conditional logistic regression analyses showed significant, dose-dependent inverse associations between the intake of vegetables, fruit or a combination of the two and the risk of NPC, even after adjustments for social-economic status, body mass index, dietary factors and other potential covariates. The adjusted odds ratios (95% confidence intervals) for NPC in the top quartile of vegetable intake, fruit intake or a combination of the two, as compared to the lowest quartile, were 0.33 (0.22–0.50), 0.70 (0.47–1.04) and 0.37 (0.25–0.55), respectively. Dark green leafy vegetables, carrots, peppers and tomatoes, citrus fruit and pome fruit showed much more pronounced benefits with regards to NPC than other types of fruit and vegetables. Interaction analyses demonstrated that the effects of total combined vegetable and fruit intake were much more significant in subjects with a higher education level (p interaction: 0.027), and the benefits of fruit were observed in males, but not in females (p interaction: 0.088).Our findings suggest that a greater consumption of fruit and vegetables may lower the risk of NPC in Chinese adults.
Starting Page	589
Ending Page	599
Page Count	11
File Format	PDF
ISSN	09575243
Journal	Cancer Causes & Control
Volume Number	23
Issue Number	4
e-ISSN	15737225
Language	English
Publisher	Springer Netherlands
Publisher Date	2012-03-06
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Nasopharyngeal carcinoma Vegetable Fruit Case–control study Chinese Cancer Research Hematology Oncology Biomedicine general Public Health/Gesundheitswesen Epidemiology
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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