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| Content Provider | Springer Nature Link |
|---|---|
| Author | Cha, Kyoung Je Kim, Dong Sung |
| Copyright Year | 2011 |
| Abstract | In this paper, we propose a novel portable and disposable pressure pump using a porous polydimethylsiloxane (PDMS) sponge and demonstrate its application to a microfluidic lab-on-a-chip. The porous PDMS sponge was simply fabricated by a sugar leaching technique based on capillary suction of pre-cured PDMS into lumps of sugar, thereby enabling us to achieve the porous PDMS sponge composed of interconnected micropores. To indicate the characteristics of the porous PDMS sponge and pump, we measured the average porosities of them whose values were 0.64 and 0.34, respectively. A stress–strain relationship of the fabricated portable pressure pump represented a linear behavior in the compressive strain range of 0 to 20%. Within this range, a pumping volume of the pressure pump could be linearly controlled by the compressed strain. Finally, the fabricated porous PDMS pump was successfully demonstrated as a portable pressure pump for a disposable microfluidic lab-on-a-chip for efficient detection of agglutination. The proposed portable pressure pump can be potentially applicable to various disposable microfluidic lab-on-a-chip systems. |
| Starting Page | 877 |
| Ending Page | 883 |
| Page Count | 7 |
| File Format | |
| ISSN | 13872176 |
| Journal | Biomedical Microdevices |
| Volume Number | 13 |
| Issue Number | 5 |
| e-ISSN | 15728781 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2011-06-23 |
| Publisher Place | Boston |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Microfluidic lab-on-a-chip Polydimethylsiloxane (PDMS) Porous PDMS sponge Portable pressure pump Sugar leaching technique Biophysics and Biological Physics Nanotechnology Biomedical Engineering Engineering Fluid Dynamics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Molecular Biology Biomedical Engineering |
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