NDLI: Plastic light coupler for absorbance detection in silicon microfluidic channels

Content Provider	Springer Nature Link
Author	Ottevaere, Heidi Overmeire, Sara Albero, Jorge Nieradko, Lukasz Desmet, Gert Gorecki, Christophe Thienpont, Hugo
Copyright Year	2014
Abstract	We present a micro-optical system for ultraviolet/visible absorbance detection in silicon microfluidic channels, which consists of a micro-optical light coupler placed on top of the silicon fluidic channel to probe the molecules under test with laser light. We use nonsequential optical ray-tracing simulations to model the system and to optimize its performance with respect to optical efficiency and system complexity. Deep Proton Writing is used to prototype the plastic light coupler and its spacer baseplate which contains marks to align the micro-optics with respect to the microfluidic channel and which allows for an accurate control of the position of the micro-optics with respect to the excitation source. We demonstrate the proof of concept of this microfluidic light probe by measuring standard samples of coumarin 102 dye with concentrations between 0.6 µM and 6 mM. Calibrating the system yields a detection limit of 4.3 µM. To conclude, we show that the concept of this microfluidic detection system is generic in that it can be applied at different positions on different microfluidic channel configurations.
Starting Page	559
Ending Page	568
Page Count	10
File Format	PDF
ISSN	16134982
Journal	Microfluidics and Nanofluidics
Volume Number	18
Issue Number	4
e-ISSN	16134990
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2014-08-08
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Absorbance detection Microfluidics Rapid prototyping Micro-optics Engineering Fluid Dynamics Biomedical Engineering Analytical Chemistry Nanotechnology and Microengineering
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Materials Chemistry Condensed Matter Physics Electronic, Optical and Magnetic Materials

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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