NDLI: AC electroosmotic flow in a DNA concentrator

Content Provider	Springer Nature Link
Author	Bown, M. R. Meinhart, C. D.
Copyright Year	2006
Abstract	Experimental velocity measurements are conducted in an AC electrokinetic DNA concentrator. The DNA concentrator is based upon Wong et al. (Transducers 2003, Boston, pp 20–23, 2003a; Anal Chem 76(23):6908–6914, 2004)and consists of two concentric electrodes that generate AC electroosmotic flow to stir the fluid, and dielectrophoretic and electrophoretic force fields that trap DNA near the centre of the inside electrode. A two-colour micro-PIV technique is used to measure the fluid velocity without a priori knowledge of the electric field in the device or the electrical properties of the particles. The device is also simulated computationally. The results indicate that the numerical simulations agree with experimental data in predicting the velocity field structure, except that the velocity scale is an order of magnitude higher for the simulations. Simulation of the dielectrophoretic forces allows the motion of the DNA within the device to be studied. It is suggested that the simulations can be used to study the phenomena occurring in the device, but that experimental data is required to determine the practical conditions under which these phenomena occur.
Starting Page	513
Ending Page	523
Page Count	11
File Format	PDF
ISSN	16134982
Journal	Microfluidics and Nanofluidics
Volume Number	2
Issue Number	6
e-ISSN	16134990
Language	English
Publisher	Springer-Verlag
Publisher Date	2006-05-20
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Micro-PIV DNA concentration AC electroosmosis Dielectrophoresis AC electrokinetics Engineering Thermodynamics, Transport Phenomena Mechanics, Fluids, Thermodynamics Nanotechnology Polymer Sciences Medical Microbiology Engineering Fluid Dynamics
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Materials Chemistry Condensed Matter Physics Electronic, Optical and Magnetic Materials

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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