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| Content Provider | Springer Nature Link |
|---|---|
| Author | Islam, N. Lian, M. Wu, J. |
| Copyright Year | 2006 |
| Abstract | Microcantilevers are finding wide applications in detecting biochemical agents. However, their usage has been limited to highly concentrated samples to ensure sufficient deposition of agents onto cantilevers. A pre-concentration or enrichment step will expand their application range to more dilute, practical samples and real-time detection. This paper reports the integration of in-situ particle concentrators on microcantilevers. Only a thin metal layer on microcantilevers is required to generate microfluidic convection of particles from solution bulk onto microcantilever surfaces, greatly enriching local particle counts and enhancing sensitivity of the system. A working prototype is presented in the paper. Preliminary experiments concentrating latex particles were conducted and the particle concentration effect has been experimentally verified using AFM probes as microcantilevers. As ACEO concentrator has no dependence on particle properties, the method is expected to be applicable to bio-particles collection. |
| Starting Page | 369 |
| Ending Page | 375 |
| Page Count | 7 |
| File Format | |
| ISSN | 16134982 |
| Journal | Microfluidics and Nanofluidics |
| Volume Number | 3 |
| Issue Number | 3 |
| e-ISSN | 16134990 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2006-11-30 |
| Publisher Place | Berlin, Heidelberg |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | AC electroosmosis Microfluidic Particle trapping Microcantilever Engineering Thermodynamics, Transport Phenomena Mechanics, Fluids, Thermodynamics Nanotechnology Polymer Sciences Medical Microbiology Engineering Fluid Dynamics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Materials Chemistry Condensed Matter Physics Electronic, Optical and Magnetic Materials |
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