WebSite Logo
  • Content
  • Similar Resources
  • Metadata
  • Cite This
  • Log-in
  • Fullscreen
Log-in
Do not have an account? Register Now
Forgot your password? Account recovery
  1. Springer Seminars in Immunopathology
  2. Springer Seminars in Immunopathology : Volume 22
  3. Springer Seminars in Immunopathology : Volume 22, Issue 1-2, March 2000
  4. The role of CpG in DNA vaccines
Loading...

Please wait, while we are loading the content...

Springer Seminars in Immunopathology : Volume 39
Springer Seminars in Immunopathology : Volume 38
Springer Seminars in Immunopathology : Volume 37
Springer Seminars in Immunopathology : Volume 36
Springer Seminars in Immunopathology : Volume 35
Springer Seminars in Immunopathology : Volume 34
Springer Seminars in Immunopathology : Volume 33
Springer Seminars in Immunopathology : Volume 32
Springer Seminars in Immunopathology : Volume 31
Springer Seminars in Immunopathology : Volume 30
Springer Seminars in Immunopathology : Volume 29
Springer Seminars in Immunopathology : Volume 28
Springer Seminars in Immunopathology : Volume 27
Springer Seminars in Immunopathology : Volume 26
Springer Seminars in Immunopathology : Volume 25
Springer Seminars in Immunopathology : Volume 24
Springer Seminars in Immunopathology : Volume 23
Springer Seminars in Immunopathology : Volume 22
Springer Seminars in Immunopathology : Volume 22, Issue 4, December 2000
Springer Seminars in Immunopathology : Volume 22, Issue 3, September 2000
Springer Seminars in Immunopathology : Volume 22, Issue 1-2, March 2000
Introduction to immunostimulatory DNA sequences
The discovery of immunostimulatory DNA sequence
Mechanisms of immune stimulation by bacterial DNA
Activation of NK cell (human and mouse) by immunostimulatory DNA sequence
Activation of skin dendritic cells by immunostimulatory DNA
Rescue of B cells from apoptosis by immune stimulatory CpG DNA
The response of human B lymphocytes to oligodeoxynucleotides
Multiple effects of immunostimulatory DNA on T cells and the role of type I interferons
Pre-priming: a novel approach to DNA-based vaccination and immunomodulation
Signal transduction induced by immunostimulatory CpG DNA
Immunostimulatory DNA sequences and cancer therapy
Modulation of asthmatic response by immunostimulatory DNA sequences
The role of CpG in DNA vaccines
Mucosal adjuvanticity of immunostimulatory DNA sequences
Immunostimulatory DNA sequences help to eradicate intracellular pathogens
The antigenic properties of bacterial DNA in normal and aberrant immunity
The role of immunostimulatory CpG-DNA in septic shock
Activation of the innate immune system by CpG oligodeoxynucleotides: immunoprotective activity and safety
Springer Seminars in Immunopathology : Volume 21
Springer Seminars in Immunopathology : Volume 20
Springer Seminars in Immunopathology : Volume 19
Springer Seminars in Immunopathology : Volume 18

Similar Documents

...
The role of immunostimulatory CpG-DNA in septic shock

Article

...
Signal transduction induced by immunostimulatory CpG DNA

Article

...
Rescue of B cells from apoptosis by immune stimulatory CpG DNA

Article

...
DNA vaccines: safety and efficacy issues

Article

...
Combination DNA plus protein HIV vaccines

Article

...
Immunization with DNA vaccines in early life: Advantages and limitations as compared to conventional vaccines

Article

...
DNA vaccines for HIV: challenges and opportunities

Article

...
Cutting Edge: Role of Toll-Like Receptor 9 in CpG DNA-Induced Activation of Human Cells

Article

...
Immunology of DNA vaccines: CpG motifs and antigen presentation

Article

The role of CpG in DNA vaccines

Content Provider Springer Nature Link
Author McCluskie, Michael J. Weeratna, Risini D. Davis, Heather L.
Copyright Year 2000
Abstract One of the most exciting developments in the field of vaccine research in recent years has been DNA vaccines, with which immune responses are induced sub-sequent to the in vivo expression of antigen from directly introduced plasmid DNA. Strong immune responses have been demonstrated in a number of animal models against many viral, bacterial and parasitic pathogens, and several human clinical trials have been undertaken. The strong and long-lasting antigen-specific humoral (antibodies) and cell-mediated (T help, other cytokine functions and cytotoxic T cells) immune responses induced by DNA vaccines appear to be due to the sustained in vivo expression of antigen, efficient antigen presentation and the presence of stimulatory CpG motifs. These features are desirable for the development of prophylactic vaccines against numerous infectious agents. Furthermore, the strong cellular responses are also very desirable for the development of therapeutic DNA vaccines to treat chronic viral infections or cancer. Efforts are now focusing on understanding the mechanisms for the induction of these immune responses, which in turn should aid in the optimization of DNA vaccines. This review will focus on the role of CpG motifs in DNA vaccines.
Starting Page 125
Ending Page 132
Page Count 8
File Format PDF
ISSN 03444325
Journal Springer Seminars in Immunopathology
Volume Number 22
Issue Number 1-2
e-ISSN 14322196
Language English
Publisher Springer-Verlag
Publisher Date 2000-01-01
Publisher Place Berlin, Heidelberg
Access Restriction Subscribed
Subject Keyword Immunology Internal Medicine
Content Type Text
Resource Type Article
Subject Immunology
  • About
  • Disclaimer
  • Feedback
  • Sponsor
  • Contact
  • Chat with Us
About National Digital Library of India (NDLI)
NDLI logo

National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.

Learn more about this project from here.

Disclaimer

NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.

Feedback

Sponsor

Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.

Contact National Digital Library of India
Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302
See location in the Map
03222 282435
Mail: support@ndl.gov.in
Sl. Authority Responsibilities Communication Details
1 Ministry of Education (GoI),
Department of Higher Education
Sanctioning Authority https://www.education.gov.in/ict-initiatives
2 Indian Institute of Technology Kharagpur Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project https://www.iitkgp.ac.in
3 National Digital Library of India Office, Indian Institute of Technology Kharagpur The administrative and infrastructural headquarters of the project Dr. B. Sutradhar  bsutra@ndl.gov.in
4 Project PI / Joint PI Principal Investigator and Joint Principal Investigators of the project Dr. B. Sutradhar  bsutra@ndl.gov.in
Prof. Saswat Chakrabarti  will be added soon
5 Website/Portal (Helpdesk) Queries regarding NDLI and its services support@ndl.gov.in
6 Contents and Copyright Issues Queries related to content curation and copyright issues content@ndl.gov.in
7 National Digital Library of India Club (NDLI Club) Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach clubsupport@ndl.gov.in
8 Digital Preservation Centre (DPC) Assistance with digitizing and archiving copyright-free printed books dpc@ndl.gov.in
9 IDR Setup or Support Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops idr@ndl.gov.in
I will try my best to help you...
Cite this Content
Loading...