NDLI: Investigation of the Origin and Spread of a Mammalian Transposable Element Based on Current Sequence Diversity

Please wait, while we are loading the content...

Is There a Twelfth Protein-Coding Gene in the Genome of Influenza A? A Selection-Based Approach to the Detection of Overlapping Genes in Closely Related Sequences

Misexpression of Testicular MicroRNA in Sterile Xenopus Hybrids Points to Tetrapod-Specific MicroRNAs Associated with Male Fertility

Two Polymorphic Residues Account for the Differences in DNA Binding and Transcriptional Activation by NF-κB Proteins Encoded by Naturally Occurring Alleles in Nematostella vectensis

A Model of Genetic Search for Beneficial Mutations: Estimating the Constructive Capacities of Mutagenesis

Molecular Characterization of Two Endothelin Pathways in East African Cichlid Fishes

Molecular Evolution of Miraculin-Like Proteins in Soybean Kunitz Super-Family

Journal of Molecular Evolution : Volume 73, Issue 3-4, October 2011

Journal of Molecular Evolution : Volume 73, Issue 1-2, August 2011

Journal of Molecular Evolution : Volume 72

Journal of Molecular Evolution : Volume 71

Journal of Molecular Evolution : Volume 70

Journal of Molecular Evolution : Volume 69

Journal of Molecular Evolution : Volume 68

Journal of Molecular Evolution : Volume 58

Journal of Molecular Evolution : Volume 53

Journal of Molecular Evolution : Volume 52

Journal of Molecular Evolution : Volume 51

Journal of Molecular Evolution : Volume 46

Journal of Molecular Evolution : Volume 44

Investigation of the Origin and Spread of a Mammalian Transposable Element Based on Current Sequence Diversity

Content Provider	Springer Nature Link
Author	Hellen, Elizabeth H. B. Brookfield, John F. Y.
Copyright Year	2012
Abstract	Almost half the human genome consists of mobile DNA elements, and their analysis is a vital part of understanding the human genome as a whole. Many of these elements are ancient and have persisted in the genome for tens or hundreds of millions of years, providing a window into the evolution of modern mammals. The Golem family have been used as model transposons to highlight computational analyses which can be used to investigate these elements, particularly the use of molecular dating with large transposon families. Whole-genome searches found Golem sequences in 20 mammalian species. Golem A and B subsequences were only found in primates and squirrel. Interestingly, the full-length Golem, found as a few copies in many mammalian genomes, was found abundantly in horse. A phylogenetic profile suggested that Golem originated after the eutherian–metatherian divergence and that the A and B subfamilies originated at a much later date. Molecular dating based on sequence diversity suggests an early age, of 175 Mya, for the origin of the family and that the A and B lineages originated much earlier than expected from their current taxonomic distribution and have subsequently been lost in some lineages. Using publically available data, it is possible to investigate the evolutionary history of transposon families. Determining in which organisms a transposon can be found is often used to date the origin and expansion of the families. However, in this analysis, molecular dating, commonly used for determining the age of gene sequences, has been used, reducing the likelihood of errors from deleted lineages.
Starting Page	287
Ending Page	296
Page Count	10
File Format	PDF
ISSN	00222844
Journal	Journal of Molecular Evolution
Volume Number	73
Issue Number	5-6
e-ISSN	14321432
Language	English
Publisher	Springer-Verlag
Publisher Date	2012-01-06
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Transposon Golem Bioinformatics Phylogeny Molecular dating Insertion Origin Mariner Plant Sciences Cell Biology Microbiology Animal Genetics and Genomics Evolutionary Biology Plant Genetics & Genomics
Content Type	Text
Resource Type	Article
Subject	Genetics Molecular Biology Ecology, Evolution, Behavior and Systematics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Investigation of the Origin and Spread of a Mammalian Transposable Element Based on Current Sequence Diversity

Investigation of the Origin and Spread of a Mammalian Transposable Element Based on Current Sequence Diversity

Investigation of the Origin and Spread of a Mammalian Transposable Element Based on Current Sequence Diversity

Phylogenetic analysis of the Tc1/mariner superfamily reveals the unexplored diversity of pogo-like elements

Transposable elements reveal a stem cell-specific class of long noncoding RNAs

The genomic landscape shaped by selection on transposable elements across 18 mouse strains

Bioinformatics and genomic analysis of transposable elements in eukaryotic genomes

Biogeography Revealed by Mariner-Like Transposable Element Sequences via a Bayesian Coalescent Approach

Recurrent insertion and duplication generate networks of transposable element sequences in the Drosophila melanogaster genome

Investigation of the Origin and Spread of a Mammalian Transposable Element Based on Current Sequence Diversity

Similar Documents

Investigation of the Origin and Spread of a Mammalian Transposable Element Based on Current Sequence Diversity

Investigation of the Origin and Spread of a Mammalian Transposable Element Based on Current Sequence Diversity

Investigation of the Origin and Spread of a Mammalian Transposable Element Based on Current Sequence Diversity

Phylogenetic analysis of the Tc1/mariner superfamily reveals the unexplored diversity of pogo-like elements

Transposable elements reveal a stem cell-specific class of long noncoding RNAs

The genomic landscape shaped by selection on transposable elements across 18 mouse strains

Bioinformatics and genomic analysis of transposable elements in eukaryotic genomes

Biogeography Revealed by Mariner-Like Transposable Element Sequences via a Bayesian Coalescent Approach

Recurrent insertion and duplication generate networks of transposable element sequences in the Drosophila melanogaster genome

Investigation of the Origin and Spread of a Mammalian Transposable Element Based on Current Sequence Diversity