NDLI: Tumor bearing decreases systemic acute inflammation in rats

Content Provider	Springer Nature Link
Author	Barbosa, A. L. R. Pinheiro, C. A. Oliveira, G. J. Moraes, M. O. Ribeiro, R. A. Vale, M. L. Souza, M. H. L. P.
Copyright Year	2009
Abstract	To investigate the effect of experimental tumor bearing on acute inflammation models in rats.Four and 7 days after Walker tumor implantation in the right armpit, carrageenan or dextran– induced edema in the contralateral paw, carrageenan induced neutrophil migration into peritoneal cavities, cutaneous vascular permeability induced by bradykinin, histamine, serotonin, substance P, capsaicin or compound 48/80, and mesenteric mast cell degranulation induced by compound 48/80 were evaluated. The control group did not receive tumor implantation. Statistical analysis was performed using one way analysis of variance (ANOVA) followed by the Bonferroni test.On the 7th day after tumor inoculation, there were significant decreases in both carrageenan and dextran- induced paw edema. Tumor bearing did not change the neutrophil infiltration induced by carrageenan. There were decreases in cutaneous vascular permeability induced by compound 48/80, serotonin or bradykinin, but not that induced by histamine, substance P. A significant inhibition of mesenteric mast cell degranulation induced by compound 48/80 was observed, on the 4th and 7th days after tumor inoculation.Tumor bearing can limit mast cell function and vascular events in acute systemic inflammation in rats, without changes in neutrophil migration.
Starting Page	235
Ending Page	240
Page Count	6
File Format	PDF
ISSN	10233830
Journal	Inflammation Research
Volume Number	58
Issue Number	5
e-ISSN	1420908X
Language	English
Publisher	Birkhäuser-Verlag
Publisher Date	2009-02-08
Publisher Place	Basel
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Tumour bearing Acute inflammation Mesenteric mast cell degranulation Immunology Pharmacology/Toxicology Rheumatology Allergology Dermatology Neurology
Content Type	Text
Resource Type	Article
Subject	Pharmacology Immunology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Mast cell degranulation prior to ischemia decreases ischemia-reperfusion injury in the canine small intestine

Decrease of cerebral mast cell degranulation after systemic administration of lipopolysaccharide

The role of mast cells in ischemia and reperfusion injury

Inhibiting mast cell degranulation by HO-1 affects dendritic cell maturation in vitro

Inhibition of degranulation and cytokine production in bone marrow-derived mast cells by hydrolyzed rice bran

Effects of endogenous substance P expression on degranulation in RBL-2H3 cells

A novel eremophilane lactone inhibits FcεRI-dependent release of pro-inflammatory mediators: structure-dependent bioactivity

In vitro inhibition of rat basophilic leukaemia mast cell (RBL-2H3) degranulation by novel indane compounds

The role of tissue mast cells in polyacrylamide gel-induced inflammation in mice

Tumor bearing decreases systemic acute inflammation in rats – role of mast cell degranulation

Similar Documents

Mast cell degranulation prior to ischemia decreases ischemia-reperfusion injury in the canine small intestine

Decrease of cerebral mast cell degranulation after systemic administration of lipopolysaccharide

The role of mast cells in ischemia and reperfusion injury

Inhibiting mast cell degranulation by HO-1 affects dendritic cell maturation in vitro

Inhibition of degranulation and cytokine production in bone marrow-derived mast cells by hydrolyzed rice bran

Effects of endogenous substance P expression on degranulation in RBL-2H3 cells

A novel eremophilane lactone inhibits FcεRI-dependent release of pro-inflammatory mediators: structure-dependent bioactivity

In vitro inhibition of rat basophilic leukaemia mast cell (RBL-2H3) degranulation by novel indane compounds

The role of tissue mast cells in polyacrylamide gel-induced inflammation in mice

Tumor bearing decreases systemic acute inflammation in rats – role of mast cell degranulation