Loading...
Please wait, while we are loading the content...
Similar Documents
Bromopyridazinedione-mediated protein and peptide bioconjugation† †Electronic supplementary information (ESI) available: Full experimental details and characterisation. See DOI: 10.1039/c1cc12807h Click here for additional data file.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chudasama, Vijay Smith, Mark Edward Brennan Schumacher, Felix F. Papaioannou, Danai Waksman, Gabriel Baker, James R. Caddick, Stephen |
| Copyright Year | 2011 |
| Abstract | Bromopyridazinedione-mediated bioconjugation to a cysteine containing protein and a disulfide containing peptide is described. The conjugates are cleavable in an excess of thiol, including cytoplasmically-relevant concentrations of glutathione, and show a high level of hydrolytic stability. The constructs have the potential for four points of chemical attachment. |
| Starting Page | 8781 |
| Ending Page | 8783 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c1cc12807h |
| PubMed reference number | 21738916 |
| Journal | Medline |
| Volume Number | 47 |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/cc/c1/c1cc12807h/c1cc12807h.pdf |
| Alternate Webpage(s) | https://doi.org/10.1039/c1cc12807h |
| Journal | Chemical communications |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |