NDLI: Évaluation de l'activité anticancéreuse in vitro et in vivo de nouveaux dérivés stéroïdiens

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Évaluation de l'activité anticancéreuse in vitro et in vivo de nouveaux dérivés stéroïdiens

Content Provider	Semantic Scholar
Author	Kenmogne, Lucie Carolle
Copyright Year	2016
Abstract	................................................................................................................................................. v Table des matières .............................................................................................................................. vii Liste des tableaux .................................................................................................................................. x Liste des schémas ............................................................................................................................... xii Liste des figures .................................................................................................................................. xiii Liste des abréviations ......................................................................................................................... xvi Dédicaces ........................................................................................................................................... xxi Remerciements .................................................................................................................................. xxii Avant-propos ..................................................................................................................................... xxiv Introduction générale ............................................................................................................................ 1 1. Généralités .................................................................................................................................... 2 1.1 Définition du cancer ................................................................................................................ 2 1.2 Stades d’évolution du cancer .................................................................................................. 2 1.3 Cancérogenèse ....................................................................................................................... 3 1.4 Facteurs de risques du cancer ................................................................................................ 4 1.5 Statistiques du cancer ............................................................................................................. 6 1.6 Traitements du cancer ............................................................................................................ 6 2. Les cancers ................................................................................................................................... 7 2.1 Cancer du sein ........................................................................................................................ 7 2.2 Cancer du poumon ................................................................................................................. 8 2.3 Leucémie ................................................................................................................................ 8 2.4 Cancer de l’ovaire ................................................................................................................... 9 2.5 Cancer du pancréas ................................................................................................................ 9 2.6 Cancer de la prostate .............................................................................................................. 9 3. La chimiothérapie anticancéreuse .............................................................................................. 10 3.1 Mode d’action des agents chimiothérapeutiques .................................................................. 10 3.2 L’apoptose ................................................................................................................................ 13 3.2.1 Voie extrinsèque ............................................................................................................ 13 3.2.2 Voie intrinsèque ............................................................................................................. 15 3.2.3 Stress du réticulum endoplasmique ............................................................................... 15 4. L’hormonothérapie anticancéreuse ............................................................................................. 17 4.1 Inhibition des enzymes de la stéroïdogenèse ....................................................................... 19 4.1.1 Inhibiteurs de la 17α-hydroxylase/17,20-lyase .............................................................. 19 4.1.2 Inhibiteurs de la stéroïde sulfatase ................................................................................ 19
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://corpus.ulaval.ca/jspui/bitstream/20.500.11794/27309/1/32767.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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