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Long-term survival and prognosis associated with conversion surgery in patients with metastatic gastric cancer
| Content Provider | Semantic Scholar |
|---|---|
| Author | Einama, Takahiro Abe, Hironori Shichi, Shunsuke Matsui, Hiroki Kanazawa, Ryo Shibuya, Kazuaki Suzuki, Takashi Matsuzawa, Fumihiko Hashimoto, Taku Kohei, Nakachi Homma, Shigenori Kawamura, Hideki Taketomi, Akinobu |
| Copyright Year | 2017 |
| Abstract | In gastric cancer, primary systemic chemotherapy is the standard approach for the management of patients with initially unresectable metastasis, and it occasionally leads to a reduction in the size of the lesion, which facilitates surgical resection. The aim of this study was to examine the prognosis of patients who were able to undergo complete resection following chemotherapy. A total of 10 patients who underwent radical surgery for stage IV primary gastric cancer after chemotherapy between 2009 and 2015 at the Department of Surgery of Hokkaido Social Work Association Obihiro Hospital (Obihiro, Japan) were retrospectively investigated. Three regimens were used (S-1, n=1; S-1 + cisplatin, n=8; and S-1 + docetaxel, n=1). The mean time from chemotherapy to surgery was 210 days. One total gastrectomy + splenectomy + colectomy, one total gastrectomy + splenectomy, four total gastrectomies and three distal gastrectomies were performed. There were two cases of pancreatic fistula formation postoperatively. All the patients survived for >1 year. Of the 10 patients, 5 survived without recurrence. The median survival time was 871.1 days after diagnosis. Therefore, curative resection after chemotherapy is associated with a better prognosis in stage IV gastric cancer patients. |
| Starting Page | 163 |
| Ending Page | 166 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.surg1-hokudai.jp/WMS_WEBALBUM/1484532138.61257600.pdf |
| Alternate Webpage(s) | https://spandidos-publications.com/mco/6/2/163/download |
| PubMed reference number | 5351747 |
| Alternate Webpage(s) | https://doi.org/10.3892/mco.2017.1128 |
| DOI | 10.3892/mco.2017.1128 |
| Journal | Molecular and clinical oncology |
| Volume Number | 6 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Cisplatin Colectomy Excision Forecast of outcome Gastrectomy Mastocytosis, Systemic Pancreatic Fistula Patients Splenectomy Stomach Carcinoma Systemic Chemotherapy docetaxel stage IV childhood Hodgkin's lymphoma unresectable |
| Content Type | Text |
| Resource Type | Article |
