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Universidade Federal De Santa Catarina Centro De Ciências Da Saúde Programa De Pós-graduação Em Farmácia
| Content Provider | Semantic Scholar |
|---|---|
| Author | Martins, Saulo Costa |
| Copyright Year | 2014 |
| Abstract | SEROPREVALENCE OF HBV MARKERS OF INFECTION AND TITLE OF anti-HBS IN INDIVIDUALS SEROPOSITIVE HIV Introduction: HIV infection and HBV are two troubling public health problems, and that HBV infection is the main global public health problem, it is estimated that there are 350 million chronic carriers of HBV. In Brazil, the prevalence of HBV is generally moderate (2 % to 7 %), with low infection rate in the South, the average rate of infection in the Northeast and Southeast and a high prevalence in the Amazon, the Espírito Santo and the western region of Santa Catarina. There are in Brazil registered 608,230 cases of AIDS since 1980, representing an average prevalence of 0.6 % of the adult population. There are currently few data are available on the prevalence of markers of infection and immunity to hepatitis B in HIV-seropositive individuals. Objectives: To determine the prevalence of markers of infection, immunity to hepatitis B virus and HBV vaccination coverage in adults confirmed HIV seropositive residents in the metropolitan region of Florianópolis. Population: The study, was conducted from October 2012 to March 2013, 300 volunteers, proven HIV seropositive. Demographic social data such as age, gender, ethnicity, education, income, time of HIV diagnosis, duration of antiretroviral therapy, most likely form of HIV infection and the results of HIV viral load and CD4 counts were obtained from patients. Results: The prevalence of HBsAg, anti-HBc was 2.3% and 29.3%, respectively. The marker of immunity anti-HBs, showed a prevalence of 56.7% in the patients studied, 43.3% of patients had a lower title than 2.0mIU/mL, in 9.7% the title was between 2.1 and 10.0mIU/mL and 47.0% greater than the title was 10.1mIU/mL. Vaccination coverage was 57.4%. Of the vaccinated patients, it was found that 15.3%, 7.7% and 34.3% had a titer of anti-HBs < 2.1mIU/mL, 2.1 to 10.0mIU/ml and > 10.1mIU/mL, respectively. Conclusions: The prevalence of HBsAg and anti-HBc showed a significant reduction when compared to those recorded in 1999, in a study done in the same area and target population results. The vaccination coverage of the population studied, 57.4% is significant, but the availability of the vaccine may be even better publicized and intensified / amplified by the Brazilian Ministry of |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://core.ac.uk/download/pdf/30405265.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
