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A low omega-6 polyunsaturated fatty acid (n-6 PUFA) diet increases omega-3 (n-3) long chain PUFA status in plasma phospholipids in humans.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wood, Katie E. Lau, Alan F. Mantzioris, Evangeline Gibson, Robert Ramsden, Christopher E. Muhlhausler, Beverly S. |
| Copyright Year | 2014 |
| Abstract | This study aimed to determine the effect of reducing the dietary linoleic acid (LA) intake from ~5% to <2.5% energy (%E) on n-3 long chain PUFA (LCPUFA) status in humans. Thirty-six participants followed a <2.5%E LA diet for 4 weeks. Nutrient intakes were estimated from diet diaries and blood samples were collected for assessment of fatty acid composition in plasma and erythrocyte phospholipids. LA intakes were reduced from 4.6%E to 2%E during the low LA intervention (P<0.001) while n-3 LCPUFA intakes were unchanged. LA and total n-6 PUFA content of plasma and erythrocyte phospholipids were significantly reduced after the low LA diet phase (P<0.001). The n-3 LCPUFA content of plasma phospholipids was significantly increased after the low LA diet compared to baseline (6.22% vs. 5.53%, P<0.001). These data demonstrate that reducing LA intake for 4 weeks increases n-3 LCPUFA status in humans in the absence of increased n-3 LCPUFA intake. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.plefa.2013.12.010 |
| PubMed reference number | 24456663 |
| Journal | Medline |
| Volume Number | 90 |
| Issue Number | 4 |
| Alternate Webpage(s) | https://digital.library.adelaide.edu.au/dspace/bitstream/2440/89590/2/hdl_89590.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/j.plefa.2013.12.010 |
| Journal | Prostaglandins, leukotrienes, and essential fatty acids |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
