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Effect of omega 3 and omega 6 fatty acid intakes from diet and supplements on plasma fatty acid levels in the first 3 years of life.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Hoyos, Camilla M. Almqvist, Catarina Garden, Frances L. Xuan, Wei Oddy, Wendy H. Marks, Guy B. Webb, Karen L. |
| Copyright Year | 2008 |
| Abstract | BACKGROUND The optimal method for conducting omega (n-)3 polyunsaturated fatty acid (PUFA) supplementation trials in children is unknown. AIM To assess the impact of n-3 and n-6 PUFA intake from the background diet on plasma levels of n-3 and n-6 PUFA in children aged 0-3 years, with and without n-3 supplementation. METHODS Subjects were randomised antenatally to receive either n-3 PUFA supplements and low n-6 PUFA cooking oils and spreads or a control intervention, designed to maintain usual fatty acid intake. Dietary intake was assessed at 18 months by 3-day weighed food record and at 3 years by food frequency questionnaire. Plasma phospholipids were measured at both time points. Associations were tested by regression. RESULTS N-3 PUFA intake from background diet did not significantly affect plasma n-3 levels. In contrast, n-6 PUFA intake in background diet was positively related to plasma n-6 levels in both study groups. In addition, n-6 PUFA intake from diet was negatively associated with plasma n-3 levels at 18 months and 3 years (-0.16%/g n-6 intake, 95%CI -0.29 to -0.03 and -0.05%/g n-6 intake, 95%CI -0.09 to -0.01, respectively) in the active group, but not in the control group. CONCLUSION Interventions intending to increase plasma n-3 PUFA in children by n-3 supplementation should also minimise n-6 PUFA intake in the background diet. |
| Starting Page | 1 |
| Ending Page | 5 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.dragaonordestino.net/Drachenwut_Blog_DragaoNordestino/Ernaehrung/fette_oele_arquivos/Effect_of_omega_3_and_omega_6.pdf |
| PubMed reference number | 19114389v1 |
| Volume Number | 17 |
| Issue Number | 4 |
| Journal | Asia Pacific journal of clinical nutrition |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Behavior Diet Dietary Supplementation Fatty Acids, Omega-6 Hearing Loss, High-Frequency Mental association Omega-3 Fatty Acids Phospholipids Polyunsaturated Fatty Acids |
| Content Type | Text |
| Resource Type | Article |
