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Genomic and molecular evolutionary analysis of a newly identified infectious agent (SEN virus) and its relationship to the TT virus family.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Tanaka, Yasuhito Primi, Daniele Wang, Richard - Umemura, Takeji Yeo, Anthony E. T. Mizokami, Masashi Alter, Harvey J. Shih, James Wai-Kuo |
| Copyright Year | 2001 |
| Abstract | A new group of transmissible single-stranded (ss) DNA viruses (SENV) distantly related to the large TT virus (TTV) family was recently identified. Eight different SENV isolates have been found, some with an association with posttransfusion hepatitis. A phylogenetic analysis of near-complete open-reading frame 1, including conserved motifs and excluding recombinant regions, was performed. The analysis used TTV-like minivirus as an outgroup, to determine a root of the phylogenetic tree, and compared 8 SENV isolates, 6 prototype TTV isolates, and 7 TTV variants (including SANBAN, TUS01, PMV, and YONBAN). Four distinct clusters separated by a bootstrap value of 100% were observed. YONBAN isolates formed a distinct outer group, representing the earliest recognized phylogenetic divergence (group 1). Prototype TTV formed group 2, PMV formed group 3, and SENV, SANBAN, and TUS01 isolates formed group 4, the most recently evolved group. This taxonomic classification suggests that these circular ssDNA viruses probably evolved from a common ancestor virus. |
| Starting Page | 4071 |
| Ending Page | 4071 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/jid/183/3/10.1086/318091/2/183-3-359.pdf?Expires=1492494294&Key-Pair-Id=APKAIUCZBIA4LVPAVW3Q&Signature=QWmhUQ2m949hjMsjwxyKP8ESCy49JQv5Jlip4NSvRdVXm6A8094gTfGmZSpSrmfZ~8ROtCeuHixURDkxQbgA0EIHdOIXRtYaTL5HTF8K8BXYkxaVPck7sVtK5zY6DXSqgxQU2XZAB64xG1SdV4KiH09kh5tDBswmZ6ZQLvMckUCF5z8jnIUdeg0zLf1wY~nOXCxMgY~dDftheY3aO-cU2ve1wjnbEEnPiKXXdNj59d4dHGFuJywET4FRg8uMBPgW4OW5JStBJgT1kgEk6qBlerMWgkW74K0mqKUkuaAlLAotp9o94OLWz~mwD-nfx7~N4nlVKmT-JkHyEVdBdBz0yw__ |
| PubMed reference number | 11133366v1 |
| Volume Number | 183 |
| Issue Number | 3 |
| Journal | The Journal of infectious diseases |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Chemical and Drug Induced Liver Injury DNA Breaks, Single-Stranded DNA, Single-Stranded Hepatitis C Mitral Valve Prolapse Syndrome Murine sarcoma viruses O'nyong-nyong Virus Parainfluenza Virus 2, Human Reading Frames (Nucleotide Sequence) Recombinants SEN virus infectious agent |
| Content Type | Text |
| Resource Type | Article |