NDLI: Ameliorative Effects of Resveratrol on Oxidative Stress Biomarkers in Horses

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Ameliorative Effects of Resveratrol on Oxidative Stress Biomarkers in Horses

Content Provider	Semantic Scholar
Author	Ememe, M. U. Mshelia, Wayuta Philip Ayo, Joseph Olusegun
Copyright Year	2015
Abstract	The aim of the present study was to evaluate the influence of age and lameness on antioxidant status in horses administered resveratrol supplement (Equithrive Joint). A total of 16 horses of both sexes, aged between 15 and 22 years, showing lameness score of 3 and weighing 350–450 kg were used, comprising eight horses which were administered resveratrol supplement for 4 weeks and eight others which served as control and given only Saccharomyces cerevisiae yeast strain used as carrier in the supplement. Blood samples were collected from each horse before supplementation (week 0) and at first, second, third, and fourth weeks of the experiment. Serum antioxidant marker of malondialdehyde (MDA) concentration, superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase activities were determined by standard methods. Resveratrol supplement administration reduced significantly (P < .05) the concentration of MDA and activity of GPx but increased that of SOD and catalase. The result showed that aging and lameness increased oxidative damage in horses, and resveratrol supplement exerted some protective effects on the aged and lame horses by increasing the antioxidant capacity of the animals. ! 2015 Elsevier Inc. All rights reserved.
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.smartpakequine.com/images/pdf/Ameliorative_Effects_of_Resveratrol.pdf
Language	English
Access Restriction	Open
Subject Keyword	3,4-Methylenedioxyamphetamine Antioxidants Biological Markers CATALASE Claudication (finding) GLUTATHIONE PEROXIDASE Hyaluronic Acid Malondialdehyde Oxidative Stress Plasma Active Saccharomyces cerevisiae Superoxide Dismutase Superoxides resveratrol
Content Type	Text
Resource Type	Article

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