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Investigation of the serum oxidative stress in broilers fed on diets supplemented with nickel chloride
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wu, Bangyuan Cui, Hengmin Peng, Xi Fang, Jing Zuo, Zhicai Deng, Junliang Huang, Jianying |
| Copyright Year | 2013 |
| Abstract | The purpose of this study was to investigate the serum oxidative stress induced by dietary nickel chloride (NiCl2) in broilers. A total of 240 oneday-old avian broilers were divided into four groups and fed on a corn-soybean basal diet as control diet or the same basal diet supplemented with 300 mg/kg, 600 mg/kg and 900 mg/kg NiCl2. During the experimental period of 42 days, oxidative stress parameters were determined for both control and experimental groups. The results showed that malondialdehyde (MDA) content was significantly higher (p < 0.05 or p < 0.01) in the 300 mg/kg, 600 mg/kg and 900 mg/kg groups than that in the control group. In contrast, the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px), and the ability to inhibit hydroxy radical, and glutathione hormone (GSH) content were significantly decreased (p < 0.05 or p < 0.01) in the 300 mg/kg, 600 mg/kg and 900 mg/kg groups in comparison with those of the control group. It was concluded that dietary NiCl2 in excess of 300 mg/kg could cause oxidative stress, which could finally impaired the antioxidant function in broilers. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://file.scirp.org/pdf/Health_2013032817073214.pdf |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | 3,4-Methylenedioxyamphetamine Antioxidants Aves Basal (phylogenetics) Basal Diet CATALASE Control Groups Dietary Nickel GLUTATHIONE PEROXIDASE Malondialdehyde Offset binary Oxidative Stress Superoxide Dismutase Superoxides hydroxyl group mg/kg nickel chloride |
| Content Type | Text |
| Resource Type | Article |
