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Comparaison du scanner 64-détecteurs et de la coronarographie dans la détection des sténoses coronariennes chez des patients porteurs d’angor stable et de syndrome coronaire aigu à bas risques
| Content Provider | Semantic Scholar |
|---|---|
| Author | Cazalas, G. Sarran, Annie Amabile, Nicolas Chaumoître, Katia Marciano-Chagnaud, S. Jacquier, Alexis Paganelli, Franck Panuel, Michel |
| Copyright Year | 2009 |
| Abstract | Purpose. To determine the accuracy of 64 MDCT coronary CTA (CCTA) compared to coronary angiography in low risk patients with stable angina and acute coronary syndrome and determine the number of significant coronary artery stenoses ( 50%) in these patients. Materials and methods. Fifty-five patients underwent CCTA using a 32 MDCT unit with z flying focus allowing the acquisition of 64 slices of 0.6 mm thickness as well as coronary angiography (gold standard). Nine patients were excluded due to prior coronary artery bypass surgery (n=4), insufficient breath hold (n=3), calcium scoring > 1000 (n=1) and delay between both examinations over 4 months (n=1). Forty-six patients: 27 males and 19 females were included. CCTA results were compared to coronary angiography per segment and artery with threshold detection of stenoses 50%. The degree of correlation between both examinations was performed using a regression analysis with a Pearson correlation coefficient Results. The overall accuracy of CCTA was 90%; limitations related to the presence of calcifications, motion artifacts or insufficient vessel opacification. The correlation for all analyzed segments was 96.4%. Thirty-eight of 50 significant stenoses seen on coronary angiography were correctly detected on CCTA. Sensitivity, specificity, PPVC and NPV for detection of stenoses 50% were 76%, 98.3%, 80.3% and 97.7% respectively. Evaluation per segment had a NPV of 96.8% (interventricular and diagonal segments) to 100% (main trunk). Conclusion. Our results for specificity and NPV are similar to reports from the literature. This suggests that CCTA in this clinical setting may replace coronary angiography. |
| Starting Page | 1055 |
| Ending Page | 1066 |
| Page Count | 12 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/S0221-0363(09)73245-7 |
| Alternate Webpage(s) | https://www.em-consulte.com/showarticlefile/225048/index.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/S0221-0363%2809%2973245-7 |
| Volume Number | 90 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
