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Prolonged hypoperfusion and early stroke after transient ischemic attack.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Bogousslavsky, Julien Ed Delaloye-Bischof, A. Regli, Franco Delaloye, Bernard |
| Copyright Year | 1990 |
| Abstract | Many patients suffer a stroke early after a transient ischemic attack, but the reason why is often unclear. We studied 12 patients with less than 75% stenosis of the internal carotid artery and a single hemispheric transient ischemic attack lasting less than 1 hour who had a normal neurologic examination 3-13 hours later and a normal computed tomogram 24-36 hours later. Single-photon emission computed tomography using technetium-99m HM-PAO less than or equal to 50 hours after the attack showed no abnormality in eight patients, but in the other four there was an area with 30-50% reduction in perfusion ipsilateral to the transient ischemic attack. Three of these four patients developed an ipsilateral infarct 3-7 days later, but none of the eight patients with normal single-photon emission computed tomograms had a stroke during the following weeks. No difference in therapy, risk factors, severity of internal carotid artery disease, or timing of the technetium-99m study could explain these findings. We suggest that some transient ischemic attacks, though clinically identical to others, may be associated with persisting focal hypoperfusion, which predisposes to early stroke. |
| Starting Page | 1321 |
| Ending Page | 1323 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://stroke.ahajournals.org/content/strokeaha/21/1/40.full.pdf |
| Alternate Webpage(s) | http://stroke.ahajournals.org/content/strokeaha/21/1/40.full.pdf?download=true |
| PubMed reference number | 2300990v1 |
| Volume Number | 21 |
| Issue Number | 1 |
| Journal | Stroke |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Arteriopathic disease Carotid Arteries Carotid Artery Diseases Cerebrovascular accident Hematopoietic System Findings Domain Infarction Internal carotid artery structure Patients Photons Stenosis Technetium 99m Tomography, Emission-Computed Transient Ischemic Attack X-Ray Computed Tomography hypoperfusion nervous system disorder |
| Content Type | Text |
| Resource Type | Article |
