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Predictive value of brain perfusion single-photon emission computed tomography in acute ischemic stroke.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Giubilei, Franco Lenzi, Gian Luigi Piero, Vittorio Di Pozzilli, Carlo Pantano, Patrizia Bastianello, Stefano Argentino, Corrado Fieschi, Cesare |
| Copyright Year | 1990 |
| Abstract | We investigated 32 patients with completed ischemic stroke less than or equal to 6 hours after the onset of symptoms by means of computed tomography, cerebral angiography, and technetium-99m-labeled hexamethylpropyleneamine oxime single-photon emission computed tomography to study cerebral blood flow. Follow-up computed tomography and cerebral blood flow studies were performed 1 week and 1 month after admission. Poor outcome at 1 month was evident in 18 (78%) of the 23 patients with severe neurologic deficit on admission and in 11 (92%) of the 12 patients with severe hypoperfusion in the affected hemisphere on admission. All 10 patients with severe impairment of both neurologic status and cerebral blood flow had a poor outcome at 1 month. We detected severe hypoperfusion in patients with large lesions on computed tomograms or cerebral artery occlusions on angiograms. Cerebral blood flow had increased at the 1-week follow-up despite different clinical outcomes. Our data provide evidence that early evaluation of cerebral blood flow with single-photon emission computed tomography is useful to detect subgroups of patients with different clinical outcomes during the acute phase of ischemic stroke. |
| Starting Page | 895 |
| Ending Page | 900 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://stroke.ahajournals.org/content/strokeaha/21/6/895.full.pdf |
| Alternate Webpage(s) | http://stroke.ahajournals.org/content/strokeaha/21/6/895.full.pdf?download=true |
| PubMed reference number | 2349593v1 |
| Volume Number | 21 |
| Issue Number | 6 |
| Journal | Stroke |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Cerebral Angiography Cerebral Arterial Diseases Cerebral Infarction Cerebrovascular Circulation Obstruction Occlusion of artery (disorder) Oximes Patients Photons Technetium Tc 99m Exametazime Tomography, Emission-Computed Tomography, Emission-Computed, Single-Photon Tracer X-Ray Computed Tomography angiogram hypoperfusion nervous system disorder |
| Content Type | Text |
| Resource Type | Article |
