NDLI: Excitotoxin lesions suggest an aspartatergic projection from rat medial prefrontal cortex to ventral tegmental area

Content Provider	Semantic Scholar
Author	Christie, Macdonald J. Bridge, S. James, Laurence B. Beart, Philip M.
Copyright Year	1985
Abstract	High affinity D-[3H]aspartate uptake and amino acid concentrations were examined in synaptosome-enriched preparations of microdissected rat ventral tegmental area 6-7 days following N-methyl-D-aspartate lesions confined to medial prefrontal cortex. Specific reductions were observed in the high affinity uptake of D-[3H]aspartate (59% of control, P less than 0.005) and concentrations of L-aspartate (79% of control, P less than 0.05) in the ventral tegmental area suggesting the presence of an aspartatergic projection from medial prefrontal cortex to this area.
Starting Page	169
Ending Page	172
Page Count	4
File Format	PDF HTM / HTML
DOI	10.1016/0006-8993(85)90140-4
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/0006899385901404
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/0006899385901404?dgcid=api_sd_search-api-endpoint
PubMed reference number	2859910
Alternate Webpage(s)	https://doi.org/10.1016/0006-8993%2885%2990140-4
Journal	Medline
Volume Number	333
Journal	Brain Research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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Excitotoxin lesions suggest an aspartatergic projection from rat medial prefrontal cortex to ventral tegmental area