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Relation of smoking and alcohol consumption to serum fatty acids.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Simon, Joel A. Fong, Josephine Bernert, J. Thomas Browner, Warren S. |
| Copyright Year | 1996 |
| Abstract | To examine the relation of cigarette smoking and alcohol consumption to serum fatty acid levels, the authors conducted a cross-sectional study of 190 men who were enrolled in the Multiple Risk Factor Intervention Trial between 1973 and 1976. After controlling for dietary fat, cholesterol, energy intake, and other potential confounders, the authors found that smoking and alcohol intake were associated with the serum cholesterol ester and phospholipid levels of several fatty acids. As the number of cigarettes smoked per day increased, the levels of cholesterol ester and phospholipid palmitoleic acid (16:1) and oleic acid (18:1) and the levels of phospholipid dihomogammalinolenic acid (20:3) and omega-9 eicosatrienoic acid (20:3) increased (all p's < or = 0.01). Serum levels of phospholipid omega-3 docosahexaenoic acid (22:6) and cholesterol ester and phospholipid arachidonic acid (20:4) were inversely associated with smoking (all p's < or = 0.01). As the number of alcoholic drinks per week increased, levels of cholesterol ester and phospholipid palmitic acid (16:0) and oleic acid (18:1), cholesterol ester myristic acid (14:0), and phospholipid palmitoleic acid (16:1), adrenic acid (22:4), and omega-9 eicosatrienoic acid (20:3) increased (all p's < 0.05), whereas levels of cholesterol ester and phospholipid linoleic acid (18:2) and phospholipid stearic acid (18:0) and the serum polyunsaturated fat: saturated fat ratio decreased (all p's < or = 0.01). These results suggest that smoking and alcohol consumption may influence the absorption, synthesis, or metabolism of serum fatty acids. Studies that use serum fatty acid levels as indicators of dietary fat intake should control for the effects of cigarette smoking and alcohol consumption. |
| Starting Page | 24 |
| Ending Page | 32 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/aje/144/4/10.1093/oxfordjournals.aje.a008933/2/144-4-325.pdf?Expires=1498602039&Key-Pair-Id=APKAIUCZBIA4LVPAVW3Q&Signature=FLCKQs2A2lY62so7JoVVpFgo44UuysVj6hCUYdAvsQBvrjY5TMkgb8CcjcYvYAk~QVN5x~zyd2xEoRIL8YzCuN74igQDqXJJ5D-r5tnMQhigFvRVx872ebtQho4-s7jGCL4AZLQ8UFJpKCgy8bUCw-KQXdpqJA0C7BiK1NkpDH2brnNSXFjkcM-oIk~0q8KIvYUaIu8grdXbLYzAypMEcjMYLNaVYUxouxngr8S~WyN~6Vght4vvjc2X3kluKXV0v0u6gN2Jyprvq31lwI6Fl4GTqVbzllkK6TZ6BoXQpMIi1cBbnRAJqHhdYztgN0DdLqs-msubKmmjdV-usCoXNw__ |
| PubMed reference number | 8712189v1 |
| Volume Number | 144 |
| Issue Number | 4 |
| Journal | American journal of epidemiology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | 8,11,14-Eicosatrienoic Acid Alcohol consumption Alcoholic Beverages Arachidonic Acid Cholesterol Esters Cigarette smoking behavior Dietary Fats Drink (dietary substance) Eicosatrienoic Acid Ethanol Fatty Acids Linoleic Acid Myristic Acid Oleic Acid Palmitic Acid Phospholipids Platelet Glycoprotein 4, human Polyunsaturated fat Salicylic Acid 20 MG/ML Medicated Liquid Soap Saturated fat Smoke Stearic acid Thioctic Acid adrenic acid docosahexaenoic acid palmitoleic acid |
| Content Type | Text |
| Resource Type | Article |