NDLI: Synthesis of new benzisoxazole derivatives and their antimicrobial, antioxidant and anti-inflammatory activities

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Synthesis of new benzisoxazole derivatives and their antimicrobial, antioxidant and anti-inflammatory activities

Content Provider	Semantic Scholar
Author	Shivaprasad, Chalya Mallappaji Jagadish, Swamy Swaroop, Toreshettahally Ramesh Mohan, Chakrabhavi Dhananjaya Roopashree, Rangaswamy Kumar, Kothanahally S. Sharath Rangappa, Kanchugarakoppal Subbegowda
Copyright Year	2014
Abstract	A series of benzisoxazole derivatives were synthesized and evaluated for their antibacterial, antioxidant and anti-inflammatory activities. The results indicated that most of the compounds exhibit moderate antimicrobial activity against Gram negative ( Escherichia coli , Klebsiella pneumoniae , Salmonella typhi , Shigella flexineri ) and Gram positive ( Bacillus subtilis ) bacterial culture. The molecules were evaluated for antioxidant activities using 2,2-diphenyl-1-picrylhydrazyl scavenging, super oxide radical scavenging and hydroxyl radical scavenging assays and most of them showed good antioxidant activities. Also, the synthesized compounds were screened for anti-inflammatory activities such as lipoxygenase inhibition and indirect haemolytic assays.
Starting Page	91
Ending Page	95
Page Count	5
File Format	PDF HTM / HTML
DOI	10.5155/eurjchem.5.1.91-95.866
Volume Number	5
Alternate Webpage(s)	http://www.eurjchem.com/index.php/eurjchem/article/download/866/PDF_866
Alternate Webpage(s)	https://doi.org/10.5155/eurjchem.5.1.91-95.866
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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