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Research article www.ijptonline.com synthesis of new anthranilic acid dyes and evaluation for their antimicrobial and anti-inflammatory activities.
| Content Provider | CiteSeerX |
|---|---|
| Author | Gaikwad, P. D. Bankar, V. H. Bodele, S. B. Mehere, A. P. |
| Abstract | Received on 31-05-2010 Accepted on 23-07-2010 A new series of dyes were synthesized from anthranilic acid derivatives by reacting p-aminobenzoic acid to HCl salt of ammonium benzoyl chloride. Then condensation of HCl salt of ammonium benzoyl chloride with anthranilic acid and its derivatives at various conditions like temperature, condition of reactants and solvents were maintained for the preparation of dyes. All the dyes were screened for antibacterial activity against S.aureus and E.coli. These dyes were also shows significant anti-inflammatory activity. The structures of new synthesized dyes were established on the basis of elemental analysis, UV, IR and NMR. Key words: Anthranilic acid, Thionyl chloride, p-aminobenzoic acid, Pyridine. |
| File Format | |
| Access Restriction | Open |
| Content Type | Text |