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Copper-catalyzed direct alkylation of heteroarenes† †Electronic supplementary information (ESI) available: Experimental procedures, characterization and copies of 1H and 13C NMR spectra for all new compounds. See DOI: 10.1039/c6sc05622a Click here for additional data file.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Theunissen, Cédric Wang, Jianjun Evano, Gwilherm |
| Copyright Year | 2017 |
| Abstract | An efficient and broadly applicable process is reported for the direct alkylation of C–H bonds in heteroarenes, privileged scaffolds in many areas of science. This reaction is based on the coppercatalyzed addition of alkyl radicals generated from activated secondary and tertiary alkyl bromides to a wide range of arenes, including furans, thiophenes, pyrroles, and their benzo-fused derivatives, as well as coumarins and quinolinones. |
| Starting Page | 3465 |
| Ending Page | 3470 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| PubMed reference number | 28507718 |
| Volume Number | 8 |
| Alternate Webpage(s) | http://pubs.rsc.org/en/content/articlepdf/2017/sc/c6sc05622a |
| Alternate Webpage(s) | https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d6/8d/SC-008-C6SC05622A.PMC5418647.pdf |
| Alternate Webpage(s) | https://pubs.rsc.org/en/content/articlepdf/2017/sc/c6sc05622a?page=search |
| Alternate Webpage(s) | https://pubs.rsc.org/en/content/articlepdf/2017/sc/c6sc05622a |
| Journal | Chemical Science |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |