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Do current indications for surgery of primary gastric lymphoma exist?
| Content Provider | Semantic Scholar |
|---|---|
| Author | Rodríguez-Sanjuán, Juan Carlos Garcia, Reynaldo A. Trugeda, Soledad Torre, Fernando De La Llorca, Javier Gómez-Fleitas, Manuel |
| Copyright Year | 2006 |
| Abstract | OBJECTIVE To analyze the results of our series in order to assess whether surgical excision is still a valid therapeutic option in case the patient needs surgery. Secondarily, to analyze Helicobacter pylori infection rate. PATIENTS AND METHOD A retrospective study of 69 consecutive patients having stage IE-IIE primary gastric lymphoma; of these, 65 were treated by gastrectomy between 1974 and 1999. Mean age: 62.6 years (28-85). New staining of paraffin-embedded samples from the surgical specimen were carried out (hematoxiline-eosine, Giemsa, immunohistochemistry) and reviewed. The histological classification was performed according to Isaacson's criteria. The statistical analysis was done by Chi-squared and Fisher's exact tests, as well as Kaplan-Meier and Log-Rank tests. RESULTS Mortality was 9.2%. There were non-fatal complications in 10.8%. Helicobacter pylori was identified in 62.7%. Seven patients (11.9%) suffered a relapse. The 5-year survival probability was 87%. The statistical analysis did not show any influences of Ann Arbor stage, gastric wall invasion, Helicobacter pylori infection, histological type, or margin resection involvement on survival. CONCLUSIONS Surgical excision provides a high rate of complete remissions and excellent long-term survival with acceptable mortality. Therefore it appears to be a valid treatment in case of emergency surgery, incidental finding, or lack of histological diagnosis. |
| Starting Page | 1 |
| Ending Page | 6 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.grupoaran.com/mrmUpdate/lecturaPDFfromXML.asp?Eng=0&IdArt=457999&TO=RVN |
| Alternate Webpage(s) | http://scielo.isciii.es/pdf/diges/v98n3/original3.pdf |
| PubMed reference number | 16737417v1 |
| Volume Number | 98 |
| Issue Number | 3 |
| Journal | Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Embedding Eosine I Bluish Eosine Yellowish Excision Gastrectomy Gastric lymphoma Giemsa stain Helicobacter pylori infection Hematoxylin Lymphoma, Non-Hodgkin Patients Specimen Staining method |
| Content Type | Text |
| Resource Type | Article |