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Helicobacter pylori Colonization in Biopsies of the Adenotonsillectomy Specimens
| Content Provider | Semantic Scholar |
|---|---|
| Author | Zahedi, Mohammad Javad Moghadam, Sodaif Darvish Mosavi, M. Ahmadi Mirshekari, T. Hayatbakhsh, Mehdi |
| Copyright Year | 2009 |
| Abstract | Problem statement: Helicobacter pylori (H. pylori) is a microaerophilic, gram negative bacillus, which can cause peptic ulcer and gastric cancer. Recurrent infection with this agent is considered as one of the reasons for failure of pep tic ulcer treatment. Some studies have reported colonization of H. pylori in dental plaques, tonsils and adenoid tissues. Th erefore oral cavity could be the source of H. pylori and it might be the reason for unsuccessful eradic ation. Approach: In this cross sectional study, 95 patients with the average age o f 12.1±7.5 years undergoing adenotonsillectomy were chosen consecutively. Intra-operatively a 2 mm sect ion of the tonsils were removed and investigated fo r H. pylori by Rapid Urease Test (RUT). Post-operatively the r emoved tonsils were stained by hematoxylin-eosin (H and E) and Gimsa for direct in vestigation of H. pylori bacterium. Serum samples of the patients were also tested for the presence o f H. pylori IgG antibody. Results: Overall 70 patients (73.7%) had positive antiH. pylori IgG antibody in their sera. The results of RUT on adeno-tonsils showed that 42.1% of the specimens were positive fo r H. pylori. In histology examination, 9 patients (9.5%) were positive for the presence of bacterium. Conclusion: Based on our findings it seems that tonsils and adenoid tissues are the candidate place s for the growth of H. pylori. Further studies about the role of tonsillar colonization of H. pylori in re-infection after treatment are recommended. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://thescipub.com/PDF/ajassp.2009.2050.2053.pdf |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Adenoidal structure Behavioral tic Biopsy Body tissue Dental Plaque Dental caries Eosine Yellowish Helicobacter pylori Hematoxylin and eosin stain method Iontophoresis Multiverse Oral cavity Palatine Tonsil Patients Peptic Ulcer Phosphoenolpyruvate Remote Utilities Specimen Stomach Carcinoma Urease adenotonsillectomy gram negative rod |
| Content Type | Text |
| Resource Type | Article |