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Prevention of coronary restenosis : the evolving evidence base for radiation therapy.

Content Provider	Semantic Scholar
Author	Kuntz, Richard E. Baim, Donald S.
Copyright Year	2000
Abstract	Restenosis, the time-limited renarrowing of the lumen of a coronary artery, affects 20% to 40% of patients in the months after an initially successful intervention.1,2 As such, it represents the extreme form of the healing response that produces a normally distributed amount of late loss in lumen diameter at all interventional sites. 3 To some extent, the percentage of patients who develop renarrowing can be reduced by acutely achieving the largest possible lumen diameter (as by stenting) via the “bigger is better” principle. Stenting can also prevent any late loss caused by vascular contraction, 4 although it does not reduce (and, in fact, increases) the amount of late loss due to excessive intimal hyperplasia. To lower the restenosis rate further and to provide durable treatment for in-stent restenosis when it occurs, potent treatments to blunt this late loss are thus required.
Starting Page	1
Ending Page	5
Page Count	5
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://citeseerx.ist.psu.edu/viewdoc/download;jsessionid=AF497C988C98C00D721BB0CDF55043CC?doi=10.1.1.503.521&rep=rep1&type=pdf
Alternate Webpage(s)	http://circ.ahajournals.org/content/circulationaha/101/18/2130.full.pdf?download=true
Alternate Webpage(s)	http://circ.ahajournals.org/content/circulationaha/101/18/2130.full.pdf
PubMed reference number	10801750v1
Volume Number	101
Issue Number	18
Journal	Circulation
Language	English
Access Restriction	Open
Subject Keyword	Blunt (object) Coronary Restenosis Diameter (qualifier value) Greater Inner Diameter Late Lumen Loss Measurement Patients Stent, device Structure of lumen of body system
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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