NDLI: Survival and degradation of Salmonella enterica serotype Enteritidis in intestinal epithelial cells in vitro.

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Survival and degradation of Salmonella enterica serotype Enteritidis in intestinal epithelial cells in vitro.

Content Provider	Semantic Scholar
Author	Saarinen, Mikael Pelliniemi, Lauri J. Granfors, K. M. -L.
Copyright Year	1996
Abstract	The survival and fate of Salmonella enterica serotype Enteritidis in Henle-407 human intestinal epithelial cells was investigated during prolonged incubation to evaluate the persistence of causative microbes and the relationship to patients developing reactive arthritis. Most of the bacteria were killed and degraded quite soon after infection of the cells, but there were still live bacteria inside the cells for up to 14 days. These results suggest that in patients developing reactive arthritis the salmonellae could persist in the epithelial cells and spread within the host to the joint and be present there at the time of the inflammatory response. Production of marked amounts of nitric oxide was observed as a novel response to salmonella infection in human intestinal epithelial cells. The present experimental procedure appears to be a suitable model to further investigate host-bacteria interaction in HLA-B27 positive cells from patients developing reactive arthritis.
Starting Page	96
Ending Page	110
Page Count	15
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://jmm.sgmjournals.org/content/45/6/463.full.pdf
Alternate Webpage(s)	http://www.microbiologyresearch.org/docserver/fulltext/jmm/45/6/medmicro-45-6-463.pdf?accname=guest&checksum=1F33A4F9C4FB332FCA54FB35AC5CABD6&expires=1544540835&id=id
PubMed reference number	8958251v1
Volume Number	45
Issue Number	6
Journal	Journal of medical microbiology
Language	English
Access Restriction	Open
Subject Keyword	Arthritis Arthritis, Reactive HLA-B27 Antigen Histocompatibility Antigens Class II Nitric Oxide Patients Salmonella enterica Salmonella infections
Content Type	Text
Resource Type	Article

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