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Initial clinical experience with extracorporeal shock wave therapy in treatment of ischemic heart failure.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Vasyuk, Yury A. Hadzegova, Alla B. Shkolnik, Evgeny L. Kopeleva, Maya V. Krikunova, Olga V. Iouchtchouk, Elena N. Aronova, Elena M. Ivanova, Svetlana Viacheslavovna |
| Copyright Year | 2010 |
| Abstract | Previous experimental studies have suggested a beneficial effect of extracorporeal shock wave therapy (ESWT) in patients with ischemic heart failure. Twenty-four patients with ischemic heart failure and left ventricular ejection fraction (LVEF) <40% received ESWT in addition to their stable treatment. ESWT was performed in 9 sessions with 100 shocks per spot in viable segments detected by dobutamine stress echocardiography. Patients were evaluated at baseline and at 3 and 6 months after ESWT. Tc-99m MIBI single photon emission computed tomography was performed on inclusion and at 6 months. ESWT significantly decreased New York Heart Association class from 2.2±0.8 to 1.7±0.7 at 3 months (P<.01) and 6 months after ESWT (1.7±0.7). Six-minute walk test improved from 414±141 to 509±141 and 538±116 (P<.01) at 3 and 6 months, respectively. A steady decrease of Canadian Cardiovascular Society angina class from 2.6±0.7 to 2.1±0.8 and 1.9±0.7 (P<.01) at 3 and 6 months, respectively, was observed. A significant increase in LVEF at rest at 3 and 6 months after ESWT (from 32.2±6.0 to 34.8±9.6 and 37.7±9.5, P=.03, respectively) was noted. Summed rest score (from 23.9±8.1 to 21.4±7.1, P=.03) and stress score improvement (from 28.2±8.4 to 24.6±6.4, P=.04) by single photon emission computed tomography was registered. Significant clinical improvement accompanied by beneficial changes of LVEF and rest/stress perfusion was found after ESWT. |
| Starting Page | 736 |
| Ending Page | 747 |
| Page Count | 12 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.nilpain.org/web-storage/webstorage4/ESWT%20for%20Congestive%20Heart%20Failure.pdf |
| PubMed reference number | 20887620v1 |
| Alternate Webpage(s) | https://doi.org/10.1111/j.1751-7133.2010.00182.x |
| DOI | 10.1111/j.1751-7133.2010.00182.x |
| Journal | Congestive heart failure |
| Volume Number | 16 |
| Issue Number | 5 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Angina Pectoris Dobutamine Echocardiography Echocardiography, Stress Ejection fraction (procedure) Heart failure Left ventricular ejection fraction Patients Photons Registration Shock Shockwave Dosing Unit Technetium Tc 99m Sestamibi Tomography, Emission-Computed Tomography, Emission-Computed, Single-Photon Ventricular Remodeling X-Ray Computed Tomography |
| Content Type | Text |
| Resource Type | Article |
