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Carboxymethyl chitosan-functionalized graphene for label-free electrochemical cytosensing
| Content Provider | Semantic Scholar |
|---|---|
| Author | Yang, Guohai Cao, Jun-Tao Li, Lingling Rana, Rohit Kumar Zhu, Jun-Jie |
| Copyright Year | 2013 |
| Abstract | Abstract Here we demonstrate the fabrication of an effective cytosensor using carboxymethyl chitosan-functionalized graphene (CMC-G) prepared through chemical reduction of graphene oxide. The CMC-G hybrid was further characterized with UV–vis spectroscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, X-ray photoelectron spectroscopy, thermogravimetric analysis, transmission electron microscopy and atomic force microscopy. Layer-by-layer assembly of CMC-G with polyethyleneimine and folic acid enabled the fabrication of a label-free electrochemical impedance spectroscopy cytosensor with high stability and biocompatibility. The proposed cytosensor exhibited good electrochemical behavior and cell-capture ability for HL-60 cells, and showed a wide linear range and low detection limit for quantification. |
| Starting Page | 124 |
| Ending Page | 133 |
| Page Count | 10 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.carbon.2012.08.020 |
| Volume Number | 51 |
| Alternate Webpage(s) | http://hysz.nju.edu.cn/jjzhu/userfiles/files/fblw/2013-3-Carboxymethyl%20chitosan-functionalized.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/j.carbon.2012.08.020 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |