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Inhaled nitric oxide therapy for acute respiratory distress syndrome in children.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Medjo, Biljana P. Atanaskovic-Markovic, Marina Nikolić, Dimitrije M. Čuturilo, Goran Djukić, Slobodanka V. |
| Copyright Year | 2012 |
| Abstract | The aim of this study was to evaluate the effects of inhaled nitric oxide (iNO) therapy on oxygenation and mortality in children with acute respiratory distress syndrome (ARDS). Thirty-three children with ARDS and an arterial SatO2 <88% despite mechanical ventilation were analyzed. Patients in the iNO group were prospectively enrolled and treated with conventional therapy plus iNO. The control group consisted of retrospectively analyzed patients treated only with conventional therapy. A significant increase in PaO2/FiO2 ratio (25.6%) and decrease in oxygenation index (19.5%) was observed after 4 h of iNO treatment, when compared to baseline values. A positive response to iNO was detected in 69% of patients, and there was no difference between pulmonary and extrapulmonary ARDS. There was no difference in mortality and duration of mechanical ventilation between iNO and control group. |
| Starting Page | 887 |
| Ending Page | 900 |
| Page Count | 14 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://imsear.li.mahidol.ac.th/bitstream/123456789/169404/1/ip2012v49n7p573.pdf |
| PubMed reference number | 22885439v1 |
| Volume Number | 49 |
| Issue Number | 7 |
| Journal | Indian pediatrics |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Cell Respiration Inspiration function Mechanical ventilation Nitric Oxide Partial Pressure Arterial Oxygen to Fraction Inspired Oxygen Ratio Measurement Patients Respiratory Distress Syndrome, Adult Sixty Nine |
| Content Type | Text |
| Resource Type | Article |