NDLI: Inhibition of nitric oxide synthase dramatically potentiates seizures induced by kainic acid and pilocarpine in rats

Content Provider	Semantic Scholar
Author	Maggio, Roberto Fumagalli, Fabio Donati, Eugenio Barbier, Pascaline Riva, Marco
Copyright Year	1995
Abstract	We investigated whether the severity of convulsions evoked by kainic acid and pilocarpine is modified in nitric oxide synthase inhibitor-treated rats. We found that chronic treatment (4 days) with NW-nitro-L-arginine greatly potentiates seizures induced by both convulsants suggesting a potential role for nitric oxide in mechanisms regulating seizure induction and propagation.
Starting Page	184
Ending Page	187
Page Count	4
File Format	PDF HTM / HTML
DOI	10.1016/0006-8993(95)00217-E
PubMed reference number	7544223
Journal	Medline
Volume Number	679
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/000689939500217E
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/000689939500217E?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://doi.org/10.1016/0006-8993%2895%2900217-E
Journal	Brain Research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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Inhibition of nitric oxide synthase dramatically potentiates seizures induced by kainic acid and pilocarpine in rats