Loading...
Please wait, while we are loading the content...
Similar Documents
7-Nitro indazole, an inhibitor of neuronal nitric oxide synthase, attenuates pilocarpine-induced seizures.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Leeuwen, R. Van Vries, René De Dzoljic, Michailo R. |
| Copyright Year | 1995 |
| Abstract | 7-Nitro indazole (25-100 mg/kg i.p.), an inhibitor of neuronal nitric oxide (NO) synthase, attenuated the severity of pilocarpine (300 mg/kg i.p.)-induced seizures in mice. This indicates that the decreased neuroexcitability of the central nervous system (CNS) following administration of 7-nitro indazole may be due to inhibition of neuronal NO synthase, implying that NO acts as an excitatory and proconvulsant factor in the CNS. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0014-2999(95)00678-8 |
| Alternate Webpage(s) | https://repub.eur.nl/pub/71386/REPUB_71386_OA.pdf |
| Alternate Webpage(s) | http://repub.eur.nl/pub/71386/REPUB_71386_OA.pdf |
| PubMed reference number | 8749039 |
| Alternate Webpage(s) | https://doi.org/10.1016/0014-2999%2895%2900678-8 |
| Journal | Medline |
| Volume Number | 287 |
| Issue Number | 2 |
| Journal | European journal of pharmacology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |