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Profile of nucleotides and nucleosides of human milk.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sugawara, Michio Sato, Nobuo Nakano, Toshiki Idota, T. Nakajima, Ikuyo |
| Copyright Year | 1995 |
| Abstract | The content of nucleotides and nucleosides of human milk was analyzed using a newly developed method for high performance liquid chromatography. By this method it is possible to analyze nucleotides and nucleosides simultaneously. Human milk was pooled according to season, lactation period, and geographical area. Three kinds of nucleosides--cytidine, uridine, and adenosine--and 6 kinds of nucleotides--5'-CMP, 5'-UMP, 5'-AMP, 5'-GMP, 5'-IMP, and 5'-CDP--were detected. Cytidine, 5'-CMP, and 5'-CDP predominated throughout lactation. Also there seemed to be geographical differences in nucleoside composition. The overall amounts of nucleotides and nucleosides were higher in winter than in summer. No nucleosides were detected in bovine milk, nor in bovine milk-based infant formula, and bovine milk contained much less nucleotides than human milk. These results suggest that nucleosides and nucleotides found in human milk may play some important roles in the development of infants. |
| Starting Page | 322 |
| Ending Page | 328 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.jstage.jst.go.jp/article/jnsv1973/41/4/41_4_409/_pdf/-char/en |
| PubMed reference number | 8676214v1 |
| Volume Number | 41 |
| Issue Number | 4 |
| Journal | Journal of nutritional science and vitaminology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Adenosine Monophosphate Cattle Contain (action) Cytidine Guanosine Monophosphate High pressure liquid chromatography procedure Infant formula Lactation Milk, Human Nucleosides Nucleotides |
| Content Type | Text |
| Resource Type | Article |