Loading...
Please wait, while we are loading the content...
Phosphorylation of nucleosides and nucleotides with inorganic monoimido-cyclo-triphosphate.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Hideko Chiba, Takeshi Tsuhako, Mitsutomo Nakayama, Hirokazu |
| Copyright Year | 2008 |
| Abstract | The phosphorylation of nucleosides (adenosine, guanosine, cytidine, and uridine) and nucleotides (adenosine 5'-monophosphate, guanosine 5'-monophosphate, cytidine 5'-monophosphate and uridine 5'-monophosphate) has been achieved using inorganic monoimido-cyclo-triphosphate (MCTP, Na(3)P(3)O(8)NH) in aqueous solution. In this reaction, the 2'-OH or 3'-OH group of the beta-D-ribofuranose unit was phosphorylated and the total yield was more than 30% and 14%, respectively. The main products were 2'-diphosphoramidophosphononucleoside and 2'-diphosphoramidophosphononucleoside 5'-monophosphate. |
| Starting Page | 758 |
| Ending Page | 758 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.jstage.jst.go.jp/article/cpb/56/12/56_12_1698/_pdf |
| PubMed reference number | 19043242v1 |
| Volume Number | 56 |
| Issue Number | 12 |
| Journal | Chemical & pharmaceutical bulletin |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Adenosine Monophosphate Adenosine Triphosphate Arabinofuranosylcytosine Triphosphate Cytidine Greater Than Guanosine Monophosphate Nucleosides Nucleotides Uridine Monophosphate beta Thalassemia |
| Content Type | Text |
| Resource Type | Article |
