NDLI: Développement d'un modèle murin de la maladie de Parkinson par augmentation compensatoire de l'arborisation axonale dopaminergique-nigrostriée

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Développement d'un modèle murin de la maladie de Parkinson par augmentation compensatoire de l'arborisation axonale dopaminergique-nigrostriée

Content Provider	Semantic Scholar
Author	Tanguay, William
Copyright Year	2017
Abstract	..................................................................................................................................... iii Table des matières...................................................................................................................... iv Liste des tableaux et graphiques ............................................................................................... vii Liste des figures .......................................................................................................................... x Liste des sigles et abréviations ................................................................................................... xi Remerciements ......................................................................................................................... xiv Avant-propos............................................................................................................................. xv Introduction ................................................................................................................................. 1 Le système dopaminergique ....................................................................................................... 3 Aspects neuroanatomiques ...................................................................................................... 4 Les neurones dopaminergiques de la SNc et la VTA ......................................................... 4 Le striatum ........................................................................................................................ 11 Aspects moléculaires ............................................................................................................ 15 La DA et ses voies de synthèse et de dégradation ............................................................ 15 La terminaison dopaminergique ....................................................................................... 15 Les récepteurs de la dopamine .......................................................................................... 16 La maladie de Parkinson ........................................................................................................... 18 Symptomatologie de la maladie de Parkinson ...................................................................... 18 Symptômes cardinaux ....................................................................................................... 19 Autres symptômes moteurs ............................................................................................... 20 Symptômes sensitifs, végétatifs et cognitifs ..................................................................... 20 Évolution clinique ............................................................................................................. 21 Diagnostic différentiel des syndromes parkinsoniens....................................................... 22 Stratégies de traitement ......................................................................................................... 23
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://papyrus.bib.umontreal.ca/xmlui/bitstream/handle/1866/18909/Tanguay_William_2016_memoire.pdf?isAllowed=y&sequence=2
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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