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Antibodies to hepatitis C virus in patients on haemodialysis.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Alonso, M. Carmen Novoa, Daniela Romero, Rafael Arcocha, V. Sánchez-Guisande, Domingo |
| Copyright Year | 1991 |
| Abstract | Dr. M.C. Alonso, Servicio de Nefrologia, Hospital Clinico Universitario, C/Galeras S/N, Santiago de Compostela (Spain) Dear Sir, Non-A, Non-B hepatitis is a common and serious consequence of blood transfusion. It has been associated with chronicity in at least half the patients with acute hepatitis and 20% of those with chronic hepatitis have histologic evidence of cirrhosis [1]. Recently a togavirus-like agent has been isolated and identified as the major etiologic virus of human non-A, non-B hepatitis [2]; this virus has been named hepatitis C (HCV); both radioim-mune and enzyme-linked assays have been developed to detect circulating antibodies to hepatitis C virus (anti-HCV) [3J. We have studied the prevalence of anti-HCV in a population of 30 patients on chronic haemodialysis using an enzyme immunoassay; the results (table 1) have been correlated with age, time on haemodialysis, number of transfusions/patient and serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and γ-glutamyltransferase. Eight patients (27%) were Table 1. Differences between anti-HCV-positive and anti-HCV-negative patients |
| Starting Page | 247 |
| Ending Page | 247 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.karger.com/Article/Pdf/186265 |
| PubMed reference number | 1850500v1 |
| Volume Number | 57 |
| Issue Number | 2 |
| Journal | Nephron |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Acute hepatitis Alanine Aspartate Transaminase Aspartic Acid Blood Transfusion CDISC SEND Chronicity Terminology Chemical and Drug Induced Liver Injury Enzyme Immunoassay Fibrosis Hemodialysis Hepatitis B Hepatitis C virus Hepatitis, Chronic Immunoenzyme Procedure Name Patients Togaviridae Transaminases non-T, non-B childhood acute lymphoblastic leukemia |
| Content Type | Text |
| Resource Type | Article |