NDLI: Development of a general methodology for labelling peptide–morpholino oligonucleotide conjugates using alkyne–azide click chemistry† †Electronic supplementary information (ESI) available: Experimental section and supplementary figures. See DOI: 10.1039/c3cc46067c Click here for additional data file.

Content Provider	Semantic Scholar
Author	Shabanpoor, Fazel Gait, Michael J.
Copyright Year	2013
Abstract	We describe a general methodology for fluorescent labelling of peptide conjugates of phosphorodiamidate morpholino oligonucleotides (PMOs) by alkyne functionalization of peptides, subsequent conjugation to PMOs and labelling with a fluorescent compound (Cy5-azide). Two peptide-PMO (PPMO) examples are shown. No detrimental effect of such labelled PMOs was seen in a biological assay.
Starting Page	10260
Ending Page	10262
Page Count	3
File Format	PDF HTM / HTML
DOI	10.1039/c3cc46067c
PubMed reference number	24064913
Journal	Medline
Volume Number	87
Alternate Webpage(s)	https://www.scienceopen.com/document_file/aeedd0f8-0dff-44eb-a698-271c3fcb46a8/PubMedCentral/aeedd0f8-0dff-44eb-a698-271c3fcb46a8.pdf
Alternate Webpage(s)	https://doi.org/10.1039/c3cc46067c
Journal	Chemical communications
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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