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The Genetics of Pediatric Nonalcoholic Fatty Liver Disease
| Content Provider | Scilit |
|---|---|
| Author | Goyal, Nidhi P. Schwimmer, Jeffrey B. |
| Copyright Year | 2017 |
| Description | Journal: Clinics in Liver Disease Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in children. Severe fibrosis and cirrhosis are potential consequences of pediatric NAFLD and can occur within a few years of diagnosis. Observations suggest that genetics may be a strong modifying factor in the presentation, severity, and natural history of the disease. There is increasing interest in determining at-risk populations based on genetics in the hope of finding genotypes that correlate to NAFLD phenotype. Ultimately, the hope is to be able to tailor therapeutics to genetic predispositions and decrease disease morbidity in children with NAFLD. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693307/pdf |
| Ending Page | 71 |
| Page Count | 13 |
| Starting Page | 59 |
| ISSN | 10893261 |
| e-ISSN | 15578224 |
| DOI | 10.1016/j.cld.2017.08.002 |
| Journal | Clinics in Liver Disease |
| Issue Number | 1 |
| Volume Number | 22 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2017-10-05 |
| Access Restriction | Open |
| Subject Keyword | Journal: Clinics in Liver Disease Pediatrics and Child Health Nonalcoholic Steatohepatitis Alanine Aminotransferase |
| Content Type | Text |
| Resource Type | Article |
| Subject | Hepatology |
