NDLI: Emerging Treatments for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

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Emerging Treatments for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

Content Provider	Scilit
Author	Gawrieh, Samer Chalasani, Naga
Copyright Year	2018
Description	Journal: Clinics in Liver Disease This review discusses completed phase II randomized clinical trials with high-quality published results for compounds that demonstrate effects on nonalcoholic steatohepatitis histology (obeticholic acid, elafibranor, and liraglutide). The authors also review the available preliminary data on cenicriviroc and selonsertib, with or without simtuzumab's phase II studies. Finally, the authors briefly discuss compounds that have been tested but did not achieve the primary end point of histologic improvement and appeared in high-quality published articles (cysteamine bitartrate and long-chain polyunsaturated fatty acids).
Related Links	https://scholarworks.iupui.edu/bitstream/1805/16121/1/Gawrieh_20217_emerging.pdf
Ending Page	199
Page Count	11
Starting Page	189
ISSN	10893261
e-ISSN	15578224
DOI	10.1016/j.cld.2017.08.013
Journal	Clinics in Liver Disease
Issue Number	1
Volume Number	22
Language	English
Publisher	Elsevier BV
Publisher Date	2018-02-01
Access Restriction	Open
Subject Keyword	Journal: Clinics in Liver Disease Gastroenterology and Hepatology
Content Type	Text
Resource Type	Article
Subject	Hepatology

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