NDLI: Development and in Vitro Evaluation of a Buccoadhesive Pindolol Tablet Formulation

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Development and in Vitro Evaluation of a Buccoadhesive Pindolol Tablet Formulation

Content Provider	Scilit
Author	Dortunç, Betül Özer, Leyla Uyanik, Nurseli
Copyright Year	1998
Description	Journal: Drug Development and Industrial Pharmacy Controlled-release buccoadhesive tablets containing pindolol were prepared and evaluated in order to achieve constant plasma concentrations during the treatment of chronic hypertension and to improve the bioavailability of pindolol by the avoidance of hepatic first-pass metabolism. The formulations were tested for weight, hardness, friability, content uniformity, swelling rate, bioadhesive force, and drug release rate values. Carbopol 934 and NaCMC were used as bioadhesive polymers and Methocel K4M, Methocel K15M, and HPC were added as matrix-forming polymers.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/03639049809085621
Ending Page	288
Page Count	8
Starting Page	281
ISSN	03639045
e-ISSN	15205762
DOI	10.3109/03639049809085621
Journal	Drug Development and Industrial Pharmacy
Issue Number	3
Volume Number	24
Language	English
Publisher	Informa UK Limited
Publisher Date	1998-01-01
Access Restriction	Open
Subject Keyword	Journal: Drug Development and Industrial Pharmacy Integrative and Complementary Medicine Pharmacology and Pharmacy Buccoadhesive
Content Type	Text
Subject	Organic Chemistry Drug Discovery Pharmacology Pharmaceutical Science

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