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SERUM INHIBIN PRO αC IN INFERTILE MEN
| Content Provider | Scilit |
|---|---|
| Author | Fujisawa, M. Yamazaki, T. Dobashi, M. Okada, H. Kamidono, S. |
| Copyright Year | 2001 |
| Description | Journal: Archives of andrology Specific assays have been developed for bioactive inhibin dimers, inhibin A and B, and inhibin f -subunit precursor pro f C. To better understand the role of serum inhibin pro f C in infertile men, the authors measured these forms of inhibin in sera from 39 infertile men and analyzed inhibin relationships with serum gonadotropins, testosterone, and estradiol. All subjects had oligozoospermia. Inhibin A levels were undetectable in all subjects. Inhibin B concentrations were 117 - 59 pg/mL. Inhibit B concentrations correlated negatively with serum FSH ( r =. 584, p <. 0001) and positively with sperm count ( p <. 01) and bilateral testicular volume ( r =. 607, p <. 0001). The concentration of pro f C was 556 - 236 pg/mL (normal range, 446 - 28). Inhibin pro f C showed no correlation with serum FSH, LH, testosterone, sperm concentration, and bilateral testicular volume. In addition, inhibin pro f C was not correlated with inhibin B. Pro f C is unlikely to be a useful marker for spermatogenesis in infertile men compared with inhibin B. |
| Related Links | https://www.tandfonline.com/doi/pdf/10.1080/014850101753145898?needAccess=true |
| Ending Page | 194 |
| Page Count | 4 |
| Starting Page | 191 |
| ISSN | 01485016 |
| e-ISSN | 15210375 |
| DOI | 10.1080/014850101753145898 |
| Journal | Archives of andrology |
| Issue Number | 3 |
| Volume Number | 47 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2001-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Archives of andrology Urology and Nephrology Infertile Men Inhibin Pro Alpha C |
| Content Type | Text |
| Subject | Endocrinology |