NDLI: Biodegradable Gelatin Microspheres for Drug Delivery to Macrophages

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Biodegradable Gelatin Microspheres for Drug Delivery to Macrophages

Content Provider	Scilit
Author	Tabata, Yasuhiko Ikada, Yoshito
Copyright Year	2020
Description	This chapter deals with carrier systems for delivery of drugs to macrophages. The ability of gelatin microspheres to enhance antibody production was greatly influenced by their extent of cross-linking, which can be varied by changing the concentration of glutaraldehyde used in their preparation. The mononuclear phagocyte system consists of circulating monocytes in the blood and macrophages in the tissue. Both types of cells are derived from myeloid progenitor cells. Macrophages play an important role in the disposal of damaged or aged cells, hematopoiesis, blood coagulation, atherogenesis, wound healing, and metal ion transport, in addition to development of immune responses and host resistance against virus-infected cells, tumors, or microorganisms. When a foreign material enters or is placed in the body, the living system initiates host defense mechanisms that involve what may be called inflammatory or immune responses. Book Name: Microparticulate Systems for the Delivery of Proteins and Vaccines
Related Links	https://content.taylorfrancis.com/books/download?dac=C2010-0-29490-7&isbn=9781003067542&doi=10.1201/9781003067542-14&format=pdf
Ending Page	423
Page Count	23
Starting Page	401
DOI	10.1201/9781003067542-14
Language	English
Publisher	Informa UK Limited
Publisher Date	2020-07-24
Access Restriction	Open
Subject Keyword	Book Name: Microparticulate Systems for the Delivery of Proteins and Vaccines Biomedical Engineering Antibody Delivery Macrophages Microorganisms Immune Responses Gelatin Microspheres
Content Type	Text
Resource Type	Chapter

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