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Structure and Antiprotozoal Activity of Triterpenoid Saponins from Glinus oppositifolius
| Content Provider | Scilit |
|---|---|
| Author | Traore, Fanta Faure, Robert Ollivier, Evelyne Gasquet, Monique Azas, Nadine Debrauwer, Laurent Keita, Arouna Timon-David, Pierre Balansard, Guy |
| Copyright Year | 2000 |
| Description | Two new triterpenoid saponins, glinosides A and B, isolated from the aerial parts of Glinus oppositifolius, have been characterized by 1D, 2D, NMR and high-resolution mass spectral (HRMS) techniques. Their structures were established respectively as 16-O-(β-arabinopyranosyl)-3-oxo-12,16β,21β,22-tetrahydroxyhopane for glinoside A and 16-O-(β-arabinopyranosyl)-3-oxo-12,16β,22-trihydroxyhopane for glinoside B. Results presented evidence that fractions had a better antiplasmodial activity $(IC_{50}$ = 31.80 μg/ml) than pure glinoside A $(IC_{50}$ = 42.30 μg/ml). |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2000-8551.pdf |
| Ending Page | 371 |
| Page Count | 4 |
| Starting Page | 368 |
| ISSN | 00320943 |
| e-ISSN | 14390221 |
| DOI | 10.1055/s-2000-8551 |
| Journal | Planta Medica |
| Issue Number | 04 |
| Volume Number | 66 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 2000-05-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Planta Medica Integrative and Complementary Medicine Triterpenoid Saponins |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Drug Discovery Analytical Chemistry Molecular Medicine Pharmacology Complementary and Alternative Medicine Pharmaceutical Science |
