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Effects of Exogenous Growth Hormone on Mammary Function in Lactating Goats
| Content Provider | Scilit |
|---|---|
| Editor | Mepham, T. B. Lawrence, S. E. Peters, A. R. Hart, I. C. |
| Copyright Year | 1984 |
| Description | The galactopoietic effect of daily injections, for five day periods, of growth hormone was examined by measuring milk yield, mammary blood flow and arteriovenous differences of glucose and amino acids on 12 occasions in four goats. In 10 periods there were marked increases (mean 18.1%) in mammary blood flow (8 statistically significant) and less-marked increases (mean 8.0%) in milk yield (6 statistically significant). On 8 of the occasions on which it was measured the maximum blood plasma growth hormone concentration was increased to more than 8 ng/ml. There were no statistically significant changes in mammary arteriovenous concentration differences of glucose or amino acids in response to growth hormone injections. It is suggested that, contrary to the usual situation in which the rate of mammary blood flow appears to be regulated by the metabolic activity of the gland, the galactopoietic response to growth hormone may be a consequence of elevated blood flow, which increases the supply to the gland of rate-limiting metabolic substrates. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-1014757.pdf |
| Ending Page | 253 |
| Page Count | 6 |
| Starting Page | 248 |
| ISSN | 00185043 |
| e-ISSN | 14394286 |
| DOI | 10.1055/s-2007-1014757 |
| Journal | Hormone and Metabolic Research |
| Issue Number | 05 |
| Volume Number | 16 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 1984-05-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Hormone and Metabolic Research Agriculture and Animal Production Key-words: Lactation Growth Hormone Mammary Gland |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry (medical) Endocrinology, Diabetes and Metabolism Biochemistry Clinical Biochemistry Endocrinology |