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High-dose dexamethasone corrects impaired myeloid-derived suppressor cell function via Ets1 in immune thrombocytopenia
| Content Provider | Scilit |
|---|---|
| Author | Hou, Yu Feng, Qi Xu, Miao Li, Guo-Sheng Liu, Xue-Na Sheng, Zi Zhou, Hai Ma, Ji Wei, Yu Sun, Yuan-Xin Yu, Ying-Yi Qiu, Ji-Hua Shao, Lin-Lin Liu, Xin-Guang Hou, Ming Peng, Jun |
| Copyright Year | 2016 |
| Description | Key Points The impaired suppressive function of myeloid-derived suppressor cells plays a role in the pathogenesis of immune thrombocytopenia. The effect of dexamethasone in correcting dysfunction of myeloid-derived suppressor cells suggests a new therapeutic mechanism of high-dose dexamethasone in patients with immune thrombocytopenia. |
| Related Links | http://www.bloodjournal.org/content/bloodjournal/127/12/1587.full.pdf |
| Ending Page | 1597 |
| Page Count | 11 |
| Starting Page | 1587 |
| DOI | 10.1182/blood-2015-10-674531 |
| Journal | Blood |
| Issue Number | 12 |
| Volume Number | 127 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2016-03-24 |
| Access Restriction | Open |
| Subject Keyword | Hematology Dysfunction Suppressor Cells High Dose Ets1 Dose Dexamethasone Myeloid Derived Journal: Blood (Vol- 121, Issue- 12) |
| Content Type | Text |
| Resource Type | Article |